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Keywords: adenine nucleotides
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Biochem J (2024) 481 (8): 587–599.
Published: 22 April 2024
... residues involved in binding adenine nucleotides at each of the three γ subunit CBS repeats of the human α2β2γ1 complex and examined their effects on regulation by AMP and ADP. Mutation of the CBS3 site has the largest effects on all three mechanisms of AMP activation, especially at lower ATP...
Includes: Supplementary data
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Biochem J (2016) 473 (2): 189–199.
Published: 05 January 2016
...Fiona A. Ross; Thomas E. Jensen; D. Grahame Hardie The γ subunits of heterotrimeric AMPK complexes contain the binding sites for the regulatory adenine nucleotides AMP, ADP and ATP. We addressed whether complexes containing different γ isoforms display different responses to adenine nucleotides...
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