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Keywords: adhesion
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Biochem J (2019) 476 (18): 2623–2655.
Published: 24 September 2019
... recognition. Correspondence: Jürgen Kopitz ( Juergen.kopitz@med.uni-heidelberg.de ) or Hans-Joachim Gabius ( gabius@tiph.vetmed.uni-muenchen.de or gabius@lectins.de ) adhesion gangliosides glycolipid glycoproteins glycosylation lectin 11 7 2019 31 8 2019 4 9 2019...
Includes: Supplementary data
Biochem J (2016) 473 (4): 435–448.
Published: 09 February 2016
...Elena O. Artemenko; Alena O. Yakimenko; Alexey V. Pichugin; Fazly I. Ataullakhanov; Mikhail A. Panteleev In resting platelets, adhesive membrane glycoproteins are attached to the cytoskeleton. On strong activation, phosphatidylserine(PS)-positive and -negative platelet subpopulations are formed...
Includes: Supplementary data
Biochem J (2015) 465 (3): 383–393.
Published: 22 January 2015
... the present study, we found mutation (R1049E) of the vinculin tail impairs its ability to bind F-actin, stimulate actin polymerization, and bundle F-actin in vitro . Further, mutant (R1049E) vinculin expressing cells are altered in cell migration, which is accompanied by changes in cell adhesion, cell...
Biochem J (2012) 442 (1): 13–25.
Published: 27 January 2012
... to its abundance in controlling cellular functions, ubiquitylation is also of key relevance to human pathologies, including cancer and inflammation. In the present review, we focus on its role in the control of cell adhesion, polarity and directional migration. It will become clear that protein...
Biochem J (2012) 441 (3): 963–970.
Published: 16 January 2012
... those with AIDS. We previously found that the AMPs (antimicrobial peptides) LL37 and hBD-3 (human β-defensin-3) inhibited C. albicans viability and its adhesion to plastic. For the present study, the mechanism by which LL37 and hBD-3 reduced C. albicans adhesion was investigated. After AMP treatment, C...
Biochem J (2011) 436 (1): 133–143.
Published: 27 April 2011
...Ivette Hernández-Negrete; Graciela B. Sala-Newby; Andras Perl; Gary R. Kunkel; Andrew C. Newby; Mark Bond Cell adhesion is essential for cell cycle progression in most normal cells. Loss of adhesion dependence is a hallmark of cellular transformation. The F-box protein Skp2 (S-phase kinase...
Includes: Supplementary data
Biochem J (2009) 420 (1): 49–56.
Published: 28 April 2009
...Chunlei Gao; Scott D. Blystone Integrin αvβ3-mediated adhesion of haemopoietic cells to vitronectin results in β3 tyrosine phosphorylation and Rho activation which is necessary for adhesion. Previously, we have shown that the RhoGEF (Rho guanine-nucleotide-exchange factor) Vav1 could associate...
Biochem J (2007) 405 (3): 417–428.
Published: 13 July 2007
... supported primary human aortic SMC (smooth-muscle cell) attachment through α5β1 and α4β1 integrins. Cells on fibulin-5 spread poorly and displayed prominent membrane ruffles but no stress fibres or focal adhesions, unlike cells on fibronectin that also binds these integrins. Cell migration and proliferation...
Biochem J (2006) 396 (1): 89–98.
Published: 26 April 2006
... cells) adhered to E-selectin-expressing CHO (Chinese-hamster ovary) cells (CHO-E), and formed homotypic aggregates when challenged by E-selectin–IgG fusion protein, by a mechanism that involved β2 integrins. Both heterotypic and homotypic PMN adhesion was accompanied by tyrosine phosphorylation of a 110...
Biochem J (2004) 380 (1): 57–65.
Published: 15 May 2004
... adhesion [Piccardoni, Sideri, Manarini, Piccoli, Martelli, de Gaetano, Cerletti and Evangelista (2001) Blood 98 , 108–116]. This suggested that an SRC-dependent outside-in signalling strengthens the β2-integrin interaction with the ligand. To support this hypothesis further, in the present study, we used...
Biochem J (2003) 375 (2): 477–488.
Published: 15 October 2003
... zonadhesin forms in gamete adhesion, we characterized the processing, activation and localization of protein in pig spermatozoa. The predominant polypeptides of processed zonadhesin were M r 300000 (p300), 105000 (p105) and 45000 (p45). p45 and p105, comprised primarily the D1, D2–D3 domains respectively...
Biochem J (2003) 372 (2): 485–493.
Published: 01 June 2003
... unclear. One possible function could be to regulate the processes of chondrocyte hypertrophy through direct cell–type X collagen interactions. Adhesions of embryonic chick chondrocytes, and cell lines with known expression of collagen-binding integrins (MG63 and HOS), were assayed on chick type X collagen...
Biochem J (2003) 369 (2): 311–318.
Published: 15 January 2003
... of the cations required for adhesion, the concentrations of LAPβ 1 required for binding and the ability of a small-molecule inhibitor of α v β 3 , SB223245, to block the interaction. Using glutathione S-transferase fusion proteins we have mapped a minimal integrin-binding loop in LAPβ 1 and then used...
Biochem J (2002) 364 (1): 65–71.
Published: 08 May 2002
... different stages of platelet adhesion on subendothelial components under flow conditions, with special attention to primary arrest. To evaluate spread platelets, samples were exposed to acetylsalicylic acid, which blocks aggregate formation. To study single platelets in contact, a monoclonal antibody...
Biochem J (2001) 359 (3): 621–629.
Published: 25 October 2001
... To whom correspondence should be addressed (e-mail sudina@genebee.msu.su ). 6 3 2001 16 7 2001 24 8 2001 The Biochemical Society, London ©2001 2001 adhesion arachidonic acid jasplakinolide leukotriene neutrophil Abbreviations used: PMN, polymorphonuclear...
Biochem J (2001) 357 (3): 843–850.
Published: 25 July 2001
...Charlotte A. LEWIS; Paul A. TOWNSEND; Clare M. ISACKE CD44 is the principal cell surface receptor for the extracellular matrix glycosaminoglycan hyaluronan, and binding to this ligand underlies CD44-mediated cell attachment and migration. As would be expected for a widely expressed adhesion...
Biochem J (2001) 355 (3): 691–697.
Published: 24 April 2001
...Makoto OSADA; Tsukasa OHMORI; Yutaka YATOMI; Kaneo SATOH; Shigemi HOSOGAYA; Yukio OZAKI Hic-5 and paxillin, members of the LIM protein family, have been shown to be localized in focal adhesion and to have a role in integrin-mediated signalling. In the present study we examined the involvement of...
Biochem J (2000) 351 (1): 79–86.
Published: 26 September 2000
...Paula STANLEY; Alison MCDOWALL; Paul A. BATES; Joanna BRASHAW; Nancy HOGG The first domain of intercellular adhesion molecule-1 (ICAM-1) binds to the leucocyte function-associated antigen-1 (LFA-1) I domain, which contains the principal ligand-binding site of this leucocyte integrin. Whether the...
Biochem J (2000) 350 (2): 485–493.
Published: 23 August 2000
... Biochemical Society, London © 2000 2000 adhesion collagen collagen I C-propeptide epitope mapping extracellular matrix Biochem. J. (2000) 350, 485 493 (Printed in Great Britain) 485 Monoclonal antibodies identify residues 199 216 of the integrin a2 vWFA domain as a functionally important region...
Biochem J (2000) 347 (2): 561–569.
Published: 10 April 2000
...Tsukasa OHMORI; Yutaka YATOMI; Naoki ASAZUMA; Kaneo SATOH; Yukio OZAKI Proline-rich tyrosine kinase 2 (Pyk2) (also known as RAFTK, CAKβ or CADTK) has been identified as a member of the focal adhesion kinase (FAK) family of protein-tyrosine kinases and it has been suggested that the mode of Pyk2...
Biochem J (2000) 345 (3): 611–619.
Published: 25 January 2000
... the accession number Y18653. 24 6 1999 29 9 1999 15 11 1999 The Biochemical Society, London © 2000 2000 adhesion bone extracellular matrix osteomyelitis serology Biochem. J. (2000) 345, 611 619 (Printed in Great Britain) 611 A bone sialoprotein-binding protein...
Biochem J (2000) 345 (2): 385–392.
Published: 10 January 2000
...Lisa D. FINKELSTEIN; Yoji SHIMIZU Cell adhesion mediated by β1 integrin receptors leads to the initiation of intracellular signals that affect cell differentiation and survival. Here we have analysed the mechanism by which the α4β1 integrin activates the mitogen-activated protein kinase pathway in...
Biochem J (1999) 344 (2): 527–533.
Published: 24 November 1999
... adjacent ninth type III repeat, which synergizes with RGD. Arg-Arg-Glu-Thr-Ala-Trp-Ala (RRETAWA) is a novel peptidic ligand for α5β1, identified by phage display, which blocks α5β1-mediated cell adhesion to fibronectin. A key question is the location of the binding sites for these ligand sequences within...
Biochem J (1999) 342 (2): 379–386.
Published: 24 August 1999
..., MD 21205, U.S.A. ( vcarruth@jhsph.edu ). 5 3 1999 18 5 1999 22 6 1999 The Biochemical Society, London © 1999 1999 adhesion parasite protozoan regulated secretion signal transduction Biochem. J. (1999) 342, 379 386 (Printed in Great Britain) 379 Ethanol and...
Biochem J (1999) 340 (1): 95–101.
Published: 10 May 1999
...-phosphatidic acid (DiC8-PA) to human eosinophils resulted in CD11b/CD18-dependent adhesion, both to STZ particles and fibronectin-coated wells, without significant upregulation of CD11b/CD18. The DiC8-PA-induced adhesion was not mediated via the fatty acid moiety, because other C8-lipids such as 1,2-diC8...
Biochem J (1999) 340 (1): 103–111.
Published: 10 May 1999
... addressed (e-mail erubin@infobiogen.fr). 13 11 1998 18 1 1999 17 2 1999 The Biochemical Society, London © 1999 1999 adhesion integrins tetraspans Biochem. J. (1999) 340, 103 111 (Printed in Great Britain) 103 Selective tetraspan integrin complexes (CD81/a4b1, CD151/a3b1...
Biochem J (1999) 339 (1): 119–125.
Published: 25 March 1999
... that a strong dynamic phosphorylation exists in serine and threonine residues of the β 2 integrins. 1 To whom correspondence should be addressed (e-mail carl.gahmberg@helsinki.fi ). 13 11 1998 4 1 1999 20 1 1999 The Biochemical Society, London © 1999 1999 adhesion...
Biochem J (1999) 338 (2): 471–478.
Published: 22 February 1999
...Marianne J. RATCLIFFE; Caroline SMALES; James M. STADDON Inflammatory mediators such as histamine and thrombin increase the tight-junction permeability of endothelial cells. Tight-junction permeability may be independently controlled, but is dependent on the adherens junction, where adhesion is...