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1-28 of 28
Keywords: adhesion
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In Collection
Editors' pick of review article highlights published in the Biochemical Journal in 2018 & 2019
Journal:
Biochemical Journal
Biochem J (2019) 476 (18): 2623–2655.
Published: 24 September 2019
...). Published by Portland Press Limited on behalf of the Biochemical Society 2019 adhesion gangliosides glycolipid glycoproteins glycosylation lectin Clearly, molecular languages of life govern cellular communication. The long and winding road that the concept of information coding by glycans...
Includes: Supplementary data
Articles
Elena O. Artemenko, Alena O. Yakimenko, Alexey V. Pichugin, Fazly I. Ataullakhanov, Mikhail A. Panteleev
Journal:
Biochemical Journal
Biochem J (2016) 473 (4): 435–448.
Published: 09 February 2016
...Elena O. Artemenko; Alena O. Yakimenko; Alexey V. Pichugin; Fazly I. Ataullakhanov; Mikhail A. Panteleev In resting platelets, adhesive membrane glycoproteins are attached to the cytoskeleton. On strong activation, phosphatidylserine(PS)-positive and -negative platelet subpopulations are formed...
Includes: Supplementary data
Articles
Karry M. Jannie, Shawn M. Ellerbroek, Dennis W. Zhou, Sophia Chen, David J. Crompton, Andrés J. García, Kris A. DeMali
Journal:
Biochemical Journal
Biochem J (2015) 465 (3): 383–393.
Published: 22 January 2015
.... In the present study, we found mutation (R1049E) of the vinculin tail impairs its ability to bind F-actin, stimulate actin polymerization, and bundle F-actin in vitro . Further, mutant (R1049E) vinculin expressing cells are altered in cell migration, which is accompanied by changes in cell adhesion, cell...
Articles
Journal:
Biochemical Journal
Biochem J (2012) 442 (1): 13–25.
Published: 27 January 2012
... to its abundance in controlling cellular functions, ubiquitylation is also of key relevance to human pathologies, including cancer and inflammation. In the present review, we focus on its role in the control of cell adhesion, polarity and directional migration. It will become clear that protein...
Articles
Journal:
Biochemical Journal
Biochem J (2012) 441 (3): 963–970.
Published: 16 January 2012
... and those with AIDS. We previously found that the AMPs (antimicrobial peptides) LL37 and hBD-3 (human β-defensin-3) inhibited C. albicans viability and its adhesion to plastic. For the present study, the mechanism by which LL37 and hBD-3 reduced C. albicans adhesion was investigated. After AMP treatment, C...
Articles
Ivette Hernández-Negrete, Graciela B. Sala-Newby, Andras Perl, Gary R. Kunkel, Andrew C. Newby, Mark Bond
Journal:
Biochemical Journal
Biochem J (2011) 436 (1): 133–143.
Published: 27 April 2011
...Ivette Hernández-Negrete; Graciela B. Sala-Newby; Andras Perl; Gary R. Kunkel; Andrew C. Newby; Mark Bond Cell adhesion is essential for cell cycle progression in most normal cells. Loss of adhesion dependence is a hallmark of cellular transformation. The F-box protein Skp2 (S-phase kinase...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2009) 420 (1): 49–56.
Published: 28 April 2009
...Chunlei Gao; Scott D. Blystone Integrin αvβ3-mediated adhesion of haemopoietic cells to vitronectin results in β3 tyrosine phosphorylation and Rho activation which is necessary for adhesion. Previously, we have shown that the RhoGEF (Rho guanine-nucleotide-exchange factor) Vav1 could associate...
Articles
Amanda C. Lomas, Kieran T. Mellody, Lyle J. Freeman, Daniel V. Bax, C. Adrian Shuttleworth, Cay M. Kielty
Journal:
Biochemical Journal
Biochem J (2007) 405 (3): 417–428.
Published: 13 July 2007
... supported primary human aortic SMC (smooth-muscle cell) attachment through α5β1 and α4β1 integrins. Cells on fibulin-5 spread poorly and displayed prominent membrane ruffles but no stress fibres or focal adhesions, unlike cells on fibronectin that also binds these integrins. Cell migration and proliferation...
Articles
Licia Totani, Antonio Piccoli, Stefano Manarini, Lorenzo Federico, Romina Pecce, Nicola Martelli, Chiara Cerletti, Paola Piccardoni, Clifford A. Lowell, Susan S. Smyth, Giorgio Berton, Virgilio Evangelista
Journal:
Biochemical Journal
Biochem J (2006) 396 (1): 89–98.
Published: 26 April 2006
... cells) adhered to E-selectin-expressing CHO (Chinese-hamster ovary) cells (CHO-E), and formed homotypic aggregates when challenged by E-selectin–IgG fusion protein, by a mechanism that involved β2 integrins. Both heterotypic and homotypic PMN adhesion was accompanied by tyrosine phosphorylation of a 110...
Articles
Paola PICCARDONI, Stefano MANARINI, Lorenzo FEDERICO, Zsuzsa BAGOLY, Romina PECCE, Nicola MARTELLI, Antonio PICCOLI, Licia TOTANI, Chiara CERLETTI, Virgilio EVANGELISTA
Journal:
Biochemical Journal
Biochem J (2004) 380 (1): 57–65.
Published: 15 May 2004
... adhesion [Piccardoni, Sideri, Manarini, Piccoli, Martelli, de Gaetano, Cerletti and Evangelista (2001) Blood 98 , 108–116]. This suggested that an SRC-dependent outside-in signalling strengthens the β2-integrin interaction with the ligand. To support this hypothesis further, in the present study, we used...
Articles
Journal:
Biochemical Journal
Biochem J (2003) 375 (2): 477–488.
Published: 15 October 2003
... of zonadhesin forms in gamete adhesion, we characterized the processing, activation and localization of protein in pig spermatozoa. The predominant polypeptides of processed zonadhesin were M r 300000 (p300), 105000 (p105) and 45000 (p45). p45 and p105, comprised primarily the D1, D2–D3 domains respectively...
Articles
Journal:
Biochemical Journal
Biochem J (2003) 372 (2): 485–493.
Published: 01 June 2003
... unclear. One possible function could be to regulate the processes of chondrocyte hypertrophy through direct cell–type X collagen interactions. Adhesions of embryonic chick chondrocytes, and cell lines with known expression of collagen-binding integrins (MG63 and HOS), were assayed on chick type X collagen...
Articles
Journal:
Biochemical Journal
Biochem J (2003) 369 (2): 311–318.
Published: 15 January 2003
... of the cations required for adhesion, the concentrations of LAPβ 1 required for binding and the ability of a small-molecule inhibitor of α v β 3 , SB223245, to block the interaction. Using glutathione S-transferase fusion proteins we have mapped a minimal integrin-binding loop in LAPβ 1 and then used...
Articles
Journal:
Biochemical Journal
Biochem J (2002) 364 (1): 65–71.
Published: 08 May 2002
... at the different stages of platelet adhesion on subendothelial components under flow conditions, with special attention to primary arrest. To evaluate spread platelets, samples were exposed to acetylsalicylic acid, which blocks aggregate formation. To study single platelets in contact, a monoclonal antibody...
Articles
Galina F. SUD'INA, Thomas G. BROCK, Marina A. PUSHKAREVA, Svetlana I. GALKINA, Denis V. TURUTIN, Marc PETERS-GOLDEN, Volker ULLRICH
Journal:
Biochemical Journal
Biochem J (2001) 359 (3): 621–629.
Published: 25 October 2001
... agent jasplakinolide, prevented the effects of sulphatides on PMN attachment and spreading and leukotriene synthesis. We conclude that shape changes occurring in response to sulphatides specifically impair PMN leukotriene synthesis by inhibiting translocation of 5-LO. adhesion arachidonic acid...
Articles
Journal:
Biochemical Journal
Biochem J (2001) 357 (3): 843–850.
Published: 25 July 2001
...Charlotte A. LEWIS; Paul A. TOWNSEND; Clare M. ISACKE CD44 is the principal cell surface receptor for the extracellular matrix glycosaminoglycan hyaluronan, and binding to this ligand underlies CD44-mediated cell attachment and migration. As would be expected for a widely expressed adhesion...
Articles
Journal:
Biochemical Journal
Biochem J (2001) 355 (3): 691–697.
Published: 24 April 2001
...Makoto OSADA; Tsukasa OHMORI; Yutaka YATOMI; Kaneo SATOH; Shigemi HOSOGAYA; Yukio OZAKI Hic-5 and paxillin, members of the LIM protein family, have been shown to be localized in focal adhesion and to have a role in integrin-mediated signalling. In the present study we examined the involvement...
Articles
Journal:
Biochemical Journal
Biochem J (2000) 351 (1): 79–86.
Published: 26 September 2000
...Paula STANLEY; Alison MCDOWALL; Paul A. BATES; Joanna BRASHAW; Nancy HOGG The first domain of intercellular adhesion molecule-1 (ICAM-1) binds to the leucocyte function-associated antigen-1 (LFA-1) I domain, which contains the principal ligand-binding site of this leucocyte integrin. Whether...
Articles
Danny S. TUCKWELL, Lyndsay SMITH, Michelle KORDA, Janet A. ASKARI, Sentot SANTOSO, Michael J. BARNES, Richard W. FARNDALE, Martin J. HUMPHRIES
Journal:
Biochemical Journal
Biochem J (2000) 350 (2): 485–493.
Published: 23 August 2000
... Society, London © 2000 2000 adhesion collagen collagen I C-propeptide epitope mapping extracellular matrix Biochem. J. (2000) 350, 485 493 (Printed in Great Britain) 485 Monoclonal antibodies identify residues 199 216 of the integrin a2 vWFA domain as a functionally important region within...
Articles
Journal:
Biochemical Journal
Biochem J (2000) 347 (2): 561–569.
Published: 10 April 2000
...Tsukasa OHMORI; Yutaka YATOMI; Naoki ASAZUMA; Kaneo SATOH; Yukio OZAKI Proline-rich tyrosine kinase 2 (Pyk2) (also known as RAFTK, CAKβ or CADTK) has been identified as a member of the focal adhesion kinase (FAK) family of protein-tyrosine kinases and it has been suggested that the mode of Pyk2...
Articles
Journal:
Biochemical Journal
Biochem J (2000) 345 (3): 611–619.
Published: 25 January 2000
... during the early steps of the infectious process. The adhesive molecules present on the cell surface of S. aureus include the collagen adhesin (Cna) [10], fibronectin-binding proteins A and B (FnBPA and FnBPB) [11], the clumping factors A and B (ClfA and ClfB), which bind fibrinogen [12,13], an elastin...
Articles
Journal:
Biochemical Journal
Biochem J (2000) 345 (2): 385–392.
Published: 10 January 2000
...Lisa D. FINKELSTEIN; Yoji SHIMIZU Cell adhesion mediated by β1 integrin receptors leads to the initiation of intracellular signals that affect cell differentiation and survival. Here we have analysed the mechanism by which the α4β1 integrin activates the mitogen-activated protein kinase pathway...
Articles
Journal:
Biochemical Journal
Biochem J (1999) 344 (2): 527–533.
Published: 24 November 1999
...) in the adjacent ninth type III repeat, which synergizes with RGD. Arg-Arg-Glu-Thr-Ala-Trp-Ala (RRETAWA) is a novel peptidic ligand for α5β1, identified by phage display, which blocks α5β1-mediated cell adhesion to fibronectin. A key question is the location of the binding sites for these ligand sequences within...
Articles
Journal:
Biochemical Journal
Biochem J (1999) 342 (2): 379–386.
Published: 24 August 1999
... attachment of the parasite to the host cell. Apical attachment coincides with the polarized discharge of parasite secretory vesicles called micro- nemes [4,5], suggesting that micronemal proteins have a role in parasite adhesion to the host cell. In a recent study with calcium ionophores, we demonstrated...
Articles
Journal:
Biochemical Journal
Biochem J (1999) 340 (1): 95–101.
Published: 10 May 1999
...-phosphatidic acid (DiC8-PA) to human eosinophils resulted in CD11b/CD18-dependent adhesion, both to STZ particles and fibronectin-coated wells, without significant upregulation of CD11b/CD18. The DiC8-PA-induced adhesion was not mediated via the fatty acid moiety, because other C8-lipids such as 1,2-diC8...
Articles
Valérie SERRU, LE NAOUR François, Martine BILLARD, David O. AZORSA, François LANZA, Claude BOUCHEIX, Eric RUBINSTEIN
Journal:
Biochemical Journal
Biochem J (1999) 340 (1): 103–111.
Published: 10 May 1999
... directly with integrins α3β1 and α6β1. Because all tetraspan-tetraspan associations are disrupted by digitonin, it is likely that the other tetraspans interact indirectly with integrins, through interactions with CD81 or CD151. adhesion integrins tetraspans Biochem. J. (1999) 340, 103 111 (Printed...
Articles
Journal:
Biochemical Journal
Biochem J (1999) 339 (1): 119–125.
Published: 25 March 1999
... that a strong dynamic phosphorylation exists in serine and threonine residues of the β 2 integrins. 1 To whom correspondence should be addressed (e-mail [email protected] ). 13 11 1998 4 1 1999 20 1 1999 The Biochemical Society, London © 1999 1999 adhesion...
Articles
Journal:
Biochemical Journal
Biochem J (1999) 338 (2): 471–478.
Published: 22 February 1999
...Marianne J. RATCLIFFE; Caroline SMALES; James M. STADDON Inflammatory mediators such as histamine and thrombin increase the tight-junction permeability of endothelial cells. Tight-junction permeability may be independently controlled, but is dependent on the adherens junction, where adhesion...