... for calpain-1 in the weaned gland after the pregnancy/lactation cycle, controlling programmed cell death and participating in the epigenetic programme during adipocyte differentiation. Total protein was extracted from snap-frozen mammary glands (0.1 g) by homogenization in a buffer containing detergents...

...-activated receptor γ), a ligand-dependent transcription factor playing a central role in adipocyte differentiation. In the luciferase reporter assay using both GAL4 chimaera and full-length PPARγ systems, a mevalonate metabolite, FPP (farnesyl pyrophosphate), which is the precursor of almost all isoprenoids...

... fide ligand for the master controller of adipocyte differentiation PPARγ (peroxisome-proliferator-activated receptor γ). This work has wide-ranging implications not only for obesity and diabetes, but also for osteoporosis and the control of circadian rhythms in which PPARγ also plays an important role...

... transcriptional networks control adipogensis, with ligand-dependent activation of PPARγ (peroxisome proliferator-activated receptor γ) being a decisive factor. Yet the identity of endogenous ligands promoting adipocyte differentiation has not been established. Here we present a critical evaluation of the role...

...-mail [email protected] ). 13 7 2001 22 10 2001 13 11 2001 The Biochemical Society, London ©2002 2002 adipocyte differentiation mitogen-activated protein kinase myogenesis neurogenesis Abbreviations used: aP2, adipocyte-specific lipid-binding protein; ATF2, activating...

[email protected] ). 2 6 1999 29 6 1999 29 7 1999 The Biochemical Society, London © 1999 1999 adipocyte differentiation gene expression preadipocyte factor Biochem. J. (1999) 343, 341 345 (Printed in Great Britain) 341 Enzymic characterization of a novel member of the regulatory B...