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Keywords: allergy
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Articles

Tick–human interactions: from allergic klendusity to the α-Gal syndrome

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Alejandro Cabezas-Cruz, Adnan Hodžić, Lourdes Mateos-Hernández, Marinela Contreras, José de la Fuente
Journal: Biochemical Journal
Biochem J (2021) 478 (9): 1783–1794.
https://doi.org/10.1042/BCJ20200915
Published: 14 May 2021
...), a type of allergy characterized by an IgE response against the carbohydrate Galα1-3Gal (α-Gal). This glycan is present in tick salivary proteins and on the surface of tick-borne pathogens such as Borrelia burgdorferi and Anaplasma phagocytophilum , the causative agents of Lyme disease and granulocytic...
View articletitled, Tick–human interactions: from allergic klendusity to the α-Gal syndrome
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Articles

Design of a heterotetravalent synthetic allergen that reflects epitope heterogeneity and IgE antibody variability to study mast cell degranulation

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Michael W. Handlogten, Tanyel Kiziltepe, Basar Bilgicer
Journal: Biochemical Journal
Biochem J (2013) 449 (1): 91–99.
https://doi.org/10.1042/BJ20121088
Published: 07 December 2012
... 11 10 2012 © The Authors Journal compilation © 2013 Biochemical Society 2013 allergy IgE antibody heterotetravalent mast cell degranulation multivalency synthetic allergen Type-1 hypersensitivity (allergic reactions) is an abnormal response of the adaptive immune system...
View articletitled, Design of a heterotetravalent synthetic allergen that reflects epitope heterogeneity and IgE antibody variability to study mast cell degranulation
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Includes: Supplementary data
Articles

Induction of group IVC phospholipase A 2 in allergic asthma: transcriptional regulation by TNFα in bronchoepithelial cells

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Justin S. Bickford, Kimberly J. Newsom, John-David Herlihy, Christian Mueller, Benjamin Keeler, Xiaolei Qiu, Jewell N. Walters, Nan Su, Shannon M. Wallet, Terence R. Flotte, Harry S. Nick
Journal: Biochemical Journal
Biochem J (2012) 442 (1): 127–137.
https://doi.org/10.1042/BJ20111269
Published: 27 January 2012
... Diagnostics, 3960 Point Eden Way, Hayward, CA 94545, U.S.A. 3 To whom correspondence should be addressed (email [email protected] ). 14 7 2011 1 11 2011 15 11 2011 15 11 2011 © The Authors Journal compilation © 2012 Biochemical Society 2012 allergy cytokine group IVC...
View articletitled, Induction of group IVC phospholipase A 2 in allergic asthma: transcriptional regulation by TNFα in bronchoepithelial cells
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Includes: Supplementary data
Articles

Targeting chemokine receptors in allergic disease

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James E. Pease
Journal: Biochemical Journal
Biochem J (2011) 434 (1): 11–24.
https://doi.org/10.1042/BJ20101132
Published: 27 January 2011
... allergy asthma chemokine G-protein-coupled receptor (GPCR) inflammation leucocyte Allergic diseases such as asthma, allergic rhinitis and atopic dermatitis are typified by an undesirable reaction to antigens (allergens) and are characterized by an influx of eosinophils, lymphocytes, basophils...
View articletitled, Targeting chemokine receptors in allergic disease
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Articles

Towards abolition of immunogenic structures in insect cells: characterization of a honey-bee ( Apis mellifera ) multi-gene family reveals both an allergy-related core α1,3-fucosyltransferase and the first insect Lewis-histo-blood-group-related antigen-synthesizing enzyme

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Dubravko Rendić, Jaroslav Klaudiny, Ute Stemmer, Julia Schmidt, Katharina Paschinger, Iain B. H. Wilson
Journal: Biochemical Journal
Biochem J (2007) 402 (1): 105–115.
https://doi.org/10.1042/BJ20060964
Published: 25 January 2007
... for the observed α1,3-fucosylation of bee-venom glycoproteins, but is expected to aid the identification and subsequent down-regulation of the FucTs in insect cell lines of biotechnological importance. allergy anti-(horseradish peroxidase) fucosyltransferase (FucT) honey-bee ( Apis mellifera ) Lewis X N...
View articletitled, Towards abolition of immunogenic structures in insect cells: characterization of a honey-bee ( Apis mellifera ) multi-gene family reveals both an allergy-related core α1,3-fucosyltransferase and the first insect Lewis-histo-blood-group-related antigen-synthesizing enzyme
Open the PDF for Towards abolition of immunogenic structures in insect cells: characterization of a honey-bee ( Apis mellifera ) multi-gene family reveals both an allergy-related core α1,3-fucosyltransferase and the first insect Lewis-histo-blood-group-related antigen-synthesizing enzyme in another window
Articles

Analysis of the cross-reactivity and of the 1.5 Å crystal structure of the Malassezia sympodialis Mala s 6 allergen, a member of the cyclophilin pan-allergen family

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Andreas G. Glaser, Andreas Limacher, Sabine Flückiger, Annika Scheynius, Leonardo Scapozza, Reto Crameri
Journal: Biochemical Journal
Biochem J (2006) 396 (1): 41–49.
https://doi.org/10.1042/BJ20051708
Published: 26 April 2006
..., GenBank® and GSDB Nucleotide Sequence Databases under the accession number AJ937743. 21 10 2005 24 1 2006 16 2 2006 16 2 2006 The Biochemical Society, London 2006 allergy Aspergillus fumigatus autoreactivity Malassezia sympodialis recombinant allergen self...
View articletitled, Analysis of the cross-reactivity and of the 1.5 Å crystal structure of the Malassezia sympodialis Mala s 6 allergen, a member of the cyclophilin pan-allergen family
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Articles

Structure and stability of 2S albumin-type peanut allergens: implications for the severity of peanut allergic reactions

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Katrin Lehmann, Kristian Schweimer, Gerald Reese, Stefanie Randow, Martin Suhr, Wolf-Meinhard Becker, Stefan Vieths, Paul Rösch
Journal: Biochemical Journal
Biochem J (2006) 395 (3): 463–472.
https://doi.org/10.1042/BJ20051728
Published: 11 April 2006
... Data Bank under accession number 1W2Q. 25 10 2005 19 12 2005 22 12 2005 22 12 2005 The Biochemical Society, London 2006 2S albumin-type peanut allergen allergy Ara h 2 Ara h 6 food allergy peanut ( Arachis hypogaea ) 1 To whom correspondence should...
View articletitled, Structure and stability of 2S albumin-type peanut allergens: implications for the severity of peanut allergic reactions
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Articles

FHL3 negatively regulates human high-affinity IgE receptor β-chain gene expression by acting as a transcriptional co-repressor of MZF-1

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Kyoko TAKAHASHI, Chiyuki MATSUMOTO, Chisei RA
Journal: Biochemical Journal
Biochem J (2005) 386 (1): 191–200.
https://doi.org/10.1042/BJ20040775
Published: 08 February 2005
... (Invitrogen) and Dulbecco's modified Eagle's medium (Sigma) respectively. All media contained 10% (v/v) fetal bovine serum (JRH Bioscience, Lenexa, KS, U.S.A.), 100 units/ml penicillin (Banyu Pharmaceutical, Tokyo, Japan) and 100 μg/ml streptomycin (Meiji Seika, Tokyo, Japan). allergy cofactor...
View articletitled, FHL3 negatively regulates human high-affinity IgE receptor β-chain gene expression by acting as a transcriptional co-repressor of MZF-1
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Articles

Molecular basis of pollen-related food allergy: identification of a second cross-reactive IgE epitope on Pru av 1, the major cherry ( Prunus avium ) allergen

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Regina WICHE, Michaela GUBESCH, Herbert KÖNIG, Kay FÖTISCH, Andreas HOFFMANN, Andrea WANGORSCH, Stephan SCHEURER, Stefan VIETHS
Journal: Biochemical Journal
Biochem J (2005) 385 (1): 319–327.
https://doi.org/10.1042/BJ20040842
Published: 14 December 2004
...Regina WICHE; Michaela GUBESCH; Herbert KÖNIG; Kay FÖTISCH; Andreas HOFFMANN; Andrea WANGORSCH; Stephan SCHEURER; Stefan VIETHS Birch ( Betula verrucosa ) pollen-associated food allergy is a well-characterized syndrome, which is due to the cross-reactivity of IgE antibodies to homologous allergens...
View articletitled, Molecular basis of pollen-related food allergy: identification of a second cross-reactive IgE epitope on Pru av 1, the major cherry ( Prunus avium ) allergen
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Articles

Mutational epitope analysis of Pru av 1 and Api g 1, the major allergens of cherry (Prunus avium) and celery (Apium graveolens): correlating IgE reactivity with three-dimensional structure

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Philipp NEUDECKER, Katrin LEHMANN, Jörg NERKAMP, Tanja HAASE, Andrea WANGORSCH, Kay FÖTISCH, Silke HOFFMANN, Paul RÖSCH, Stefan VIETHS, Stephan SCHEURER
Journal: Biochemical Journal
Biochem J (2003) 376 (1): 97–107.
https://doi.org/10.1042/bj20031057
Published: 15 November 2003
... 7 2003 20 8 2003 28 8 2003 28 8 2003 The Biochemical Society, London ©2003 2003 allergen structure allergy cross-reactivity hypoallergenic mutants IgE-epitope analysis Abbreviations used: 1D/2D/3D, one-/two-/three-dimensional; EAST, enzyme allergosorbent test...
View articletitled, Mutational epitope analysis of Pru av 1 and Api g 1, the major allergens of cherry (Prunus avium) and celery (Apium graveolens): correlating IgE reactivity with three-dimensional structure
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Articles

Correlating IgE reactivity with three-dimensional structure

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Reto CRAMERI
Journal: Biochemical Journal
Biochem J (2003) 376 (1): e1–e2.
https://doi.org/10.1042/bj20031363
Published: 15 November 2003
... about the therapeutic usefulness of conventional site-directed-mutagenic approaches for the production of hypo-allergenic protein variants. 1 e-mail [email protected] 8 9 2003 9 9 2003 10 11 2003 The Biochemical Society, London ©2003 2003 allergy cross-reactivity...
View articletitled, Correlating IgE reactivity with three-dimensional structure
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Articles

Molecular characterization of recombinant T1, a non-allergenic periwinkle (Catharanthus roseus) protein, with sequence similarity to the Bet v 1 plant allergen family

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Sylvia LAFFER, Said HAMDI, Christian LUPINEK, Wolfgang R. SPERR, Peter VALENT, Petra VERDINO, Walter KELLER, Monika GROTE, Karin HOFFMANN-SOMMERGRUBER, Otto SCHEINER, Dietrich KRAFT, Marc RIDEAU, Rudolf VALENTA
Journal: Biochemical Journal
Biochem J (2003) 373 (1): 261–269.
https://doi.org/10.1042/bj20030331
Published: 01 July 2003
...Sylvia LAFFER; Said HAMDI; Christian LUPINEK; Wolfgang R. SPERR; Peter VALENT; Petra VERDINO; Walter KELLER; Monika GROTE; Karin HOFFMANN-SOMMERGRUBER; Otto SCHEINER; Dietrich KRAFT; Marc RIDEAU; Rudolf VALENTA More than 25% of the population suffer from Type I allergy, an IgE-mediated...
View articletitled, Molecular characterization of recombinant T1, a non-allergenic periwinkle (Catharanthus roseus) protein, with sequence similarity to the Bet v 1 plant allergen family
Open the PDF for Molecular characterization of recombinant T1, a non-allergenic periwinkle (Catharanthus roseus) protein, with sequence similarity to the Bet v 1 plant allergen family in another window
Articles

Cloning and expression of biologically active Plantago lanceolata pollen allergen Pla l 1 in the yeast Pichia pastoris

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Belén CALABOZO, Araceli DÍAZ-PERALES, Gabriel SALCEDO, Domingo BARBER, Florentino POLO
Journal: Biochemical Journal
Biochem J (2003) 372 (3): 889–896.
https://doi.org/10.1042/bj20021491
Published: 15 June 2003
... 19 3 2003 The Biochemical Society, London ©2003 2003 allergy English plantain pollinosis recombinant allergen ribwort Abbreviations used: DSA, Datura stramonium agglutinin; GNA, Galanthus nivalis agglutinin; IUIS, International Union of Immunological Societies; MAA...
View articletitled, Cloning and expression of biologically active Plantago lanceolata pollen allergen Pla l 1 in the yeast Pichia pastoris
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Articles

Tumour-necrosis-factor-receptor-associated factor 6, NF-κB-inducing kinase and IκB kinases mediate IgE isotype switching in response to CD40

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Kevin BRADY, Stephen FITZGERALD, Paul N. MOYNAGH
Journal: Biochemical Journal
Biochem J (2000) 350 (3): 735–740.
https://doi.org/10.1042/bj3500735
Published: 08 September 2000
... 13 6 2000 30 6 2000 The Biochemical Society, London © 2000 2000 allergy B-cells kinases nuclear factor B signal transduction Biochem. J. (2000) 350, 735 740 (Printed in Great Britain) 735 Tumour-necrosis-factor-receptor-associated factor 6, NF-jB-inducing kinase and IjB...
View articletitled, Tumour-necrosis-factor-receptor-associated factor 6, NF-κB-inducing kinase and IκB kinases mediate IgE isotype switching in response to CD40
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