... Rubio (email [email protected] ). 17 6 2009 11 9 2009 15 9 2009 15 9 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 acetylglutamate allosteric site carbamoyl phosphate synthetase deficiency carglumic acid N -carbamoyl- L -glutamate urea...

... and in a position to interact with the β- and γ-phosphates of ATP. A SO 4 2− ion, an analogue of the activator phosphate, was found to bind at both the R5P-binding site and the allosteric site defined previously. In addi-tion, an extra SO 4 2− binds at a site at the dimer interface between the ATP-binding site...