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Keywords: amino acid deprivation
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Activating transcription factor 4-dependent induction of FGF21 during amino acid deprivation
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2012) 443 (1): 165–171.
Published: 14 March 2012
... shown that FGF21 is induced by amino acid deprivation in both mouse liver and cultured HepG2 cells. We have identified the human FGF21 gene as a target gene for ATF4 and we have localized two conserved ATF4-binding sequences in the 5′ regulatory region of the human FGF21 gene, which are responsible...
