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Keywords: antimicrobial peptides
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Articles
Multistep optimization of a cell-penetrating peptide towards its antimicrobial activity
Available to PurchaseMarco Drexelius, Andre Reinhardt, Joshua Grabeck, Tom Cronenberg, Frank Nitsche, Pitter F. Huesgen, Berenike Maier, Ines Neundorf
Journal:
Biochemical Journal
Biochem J (2021) 478 (1): 63–78.
Published: 08 January 2021
... for the everlasting demand of new antibiotic compounds constitute antimicrobial peptides (AMPs). These peptides act against different types of microbes by permeabilizing pathogen cell membranes, whereas being harmless to mammalian cells. Contrarily, another class of membrane-active peptides, namely cell-penetrating...
Includes: Supplementary data
Articles
Mechanisms of biofilm inhibition and degradation by antimicrobial peptides
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2015) 468 (2): 259–270.
Published: 22 May 2015
... extracellular polymeric substance (EPS), leading to bacterial resistance to antibiotics. Antimicrobial peptides (AMPs) are extensively studied with regard to planktonic bacteria but much less so with regard to biofilm formation. In the present study, we investigated how the above three steps are affected...
Includes: Supplementary data