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Articles

The atypical thioredoxin ‘Alr2205’, a newly identified partner of the typical 2-Cys-Peroxiredoxin, safeguards the cyanobacterium Anabaena from oxidative stress

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Manisha Banerjee, Namrata Waghamare, Prakash Kalwani, Deepak T. Hurali, Rachna Agarwal, Anand Ballal
Journal: Biochemical Journal
Biochem J (2023) 480 (1): 87–104.
https://doi.org/10.1042/BCJ20220524
Published: 13 January 2023
... in prokaryotes. Correspondence: Manisha Banerjee ( [email protected] ) or Anand Ballal ( [email protected] ) 22 10 2022 20 12 2022 3 1 2023 © 2023 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2023 antioxidants molecular...
View articletitled, The atypical thioredoxin ‘Alr2205’, a newly identified partner of the typical 2-Cys-Peroxiredoxin, safeguards the cyanobacterium Anabaena from oxidative stress
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Includes: Supplementary data
Articles

Ascorbate protects the diheme enzyme, MauG, against self-inflicted oxidative damage by an unusual antioxidant mechanism

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Zhongxin Ma, Victor L. Davidson
Journal: Biochemical Journal
Biochem J (2017) 474 (15): 2563–2572.
https://doi.org/10.1042/BCJ20170349
Published: 18 July 2017
... be a previously unrecognized mechanism by which ascorbate mitigates oxidative damage to heme-dependent enzymes and redox proteins in nature. © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2017 antioxidants cytochrome electron transfer oxidative stress...
View articletitled, Ascorbate protects the diheme enzyme, MauG, against self-inflicted oxidative damage by an unusual antioxidant mechanism
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Articles

Efficacy of safranal to cisplatin-induced nephrotoxicity

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Yasemin Sunucu Karafakıoğlu, Mehmet Fatih Bozkurt, Ömer Hazman, A. Fatih Fıdan
Journal: Biochemical Journal
Biochem J (2017) 474 (7): 1195–1203.
https://doi.org/10.1042/BCJ20160971
Published: 20 March 2017
... of malondialdehyde (MDA) and glutathione (GSH) as well as total antioxidant status (TAS) and total oxidant status (TOS) were determined in kidney tissue. Administration of cisplatin to rats induced a marked renal failure, characterized with a significant increase in plasma creatinine and urea concentrations. MDA...
View articletitled, Efficacy of safranal to cisplatin-induced nephrotoxicity
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Articles

KEAP1–NRF2 signalling and autophagy in protection against oxidative and reductive proteotoxicity

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Matthew Dodson, Matthew Redmann, Namakkal S. Rajasekaran, Victor Darley-Usmar, Jianhua Zhang
Journal: Biochemical Journal
Biochem J (2015) 469 (3): 347–355.
https://doi.org/10.1042/BJ20150568
Published: 23 July 2015
... redox networks by KEAP1–NRF2 induces a reductive stress, by decreasing the lifetime of necessary oxidative post-translational modifications required for normal metabolism or cell signalling. In this context, it is now becoming clear why antioxidants or hyperactivation of antioxidant pathways...
View articletitled, KEAP1–NRF2 signalling and autophagy in protection against oxidative and reductive proteotoxicity
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Articles

Induction of metallothionein I by phenolic antioxidants requires metal-activated transcription factor 1 (MTF-1) and zinc

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Yongyi BI, Richard D. PALMITER, Kristi M. WOOD, Qiang MA
Journal: Biochemical Journal
Biochem J (2004) 380 (3): 695–703.
https://doi.org/10.1042/bj20031677
Published: 15 June 2004
...Yongyi BI; Richard D. PALMITER; Kristi M. WOOD; Qiang MA Phenolic antioxidants, such as tBHQ [2,5-di-(t-butyl)-1,4-hydroquinone], induce Mt1 (metallothionein 1) gene expression and accumulation of MT protein. Induction of Mt1 mRNA does not depend on protein synthesis, and correlates with oxidation...
View articletitled, Induction of metallothionein I by phenolic antioxidants requires metal-activated transcription factor 1 (MTF-1) and zinc
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Articles

Induction of glutathione synthesis by oxidized low-density lipoprotein and 1-palmitoyl-2-arachidonyl phosphatidylcholine: protection against quinone-mediated oxidative stress

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Douglas R. MOELLERING, Anna-Liisa LEVONEN, Young-Mi GO, Rakesh P. PATEL, Dale A. DICKINSON, Henry Jay FORMAN, Victor M. DARLEY-USMAR
Journal: Biochemical Journal
Biochem J (2002) 362 (1): 51–59.
https://doi.org/10.1042/bj3620051
Published: 08 February 2002
...Douglas R. MOELLERING; Anna-Liisa LEVONEN; Young-Mi GO; Rakesh P. PATEL; Dale A. DICKINSON; Henry Jay FORMAN; Victor M. DARLEY-USMAR Exposure of endothelial cells to oxidized low-density lipoprotein (oxLDL) leads to diverse cellular effects, including induction of the intracellular antioxidant GSH...
View articletitled, Induction of glutathione synthesis by oxidized low-density lipoprotein and 1-palmitoyl-2-arachidonyl phosphatidylcholine: protection against quinone-mediated oxidative stress
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Articles

Haem oxygenase shows pro-oxidant activity in microsomal and cellular systems: implications for the release of low-molecular-mass iron

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Nicholas J. LAMB, Gregory J. QUINLAN, Sharon MUMBY, Timothy W. EVANS, John M. C. GUTTERIDGE
Journal: Biochemical Journal
Biochem J (1999) 344 (1): 153–158.
https://doi.org/10.1042/bj3440153
Published: 08 November 1999
...Nicholas J. LAMB; Gregory J. QUINLAN; Sharon MUMBY; Timothy W. EVANS; John M. C. GUTTERIDGE Haem oxygenase-1 (HO-1) is a highly inducible stress protein that removes haem from cells with the release of biliverdin, carbon monoxide and low-molecular-mass iron (LMrFe). Several antioxidant functions...
View articletitled, Haem oxygenase shows pro-oxidant activity in microsomal and cellular systems: implications for the release of low-molecular-mass iron
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Articles

The 5-lipoxygenase-activating protein (FLAP) inhibitor, MK886, induces apoptosis independently of FLAP

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Kaushik DATTA, Shyam S. BISWAL, James P. KEHRER
Journal: Biochemical Journal
Biochem J (1999) 340 (2): 371–375.
https://doi.org/10.1042/bj3400371
Published: 25 May 1999
...-mail [email protected]). 19 2 1999 1 4 1999 9 4 1999 The Biochemical Society, London © 1999 1999 antioxidants apoptosis bax bcl-x L Biochem. J. (1999) 340, 371 375 (Printed in Great Britain) 371 RESEARCH COMMUNICATION The 5-lipoxygenase-activating protein (FLAP...
View articletitled, The 5-lipoxygenase-activating protein (FLAP) inhibitor, MK886, induces apoptosis independently of FLAP
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Articles

When and why a water-soluble antioxidant becomes pro-oxidant during copper-induced low-density lipoprotein oxidation: a study using uric acid

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Marco BAGNATI, Cristina PERUGINI, Cristiana CAU, Roberta BORDONE, Emanuele ALBANO, Giorgio BELLOMO
Journal: Biochemical Journal
Biochem J (1999) 340 (1): 143–152.
https://doi.org/10.1042/bj3400143
Published: 10 May 1999
...Marco BAGNATI; Cristina PERUGINI; Cristiana CAU; Roberta BORDONE; Emanuele ALBANO; Giorgio BELLOMO The inclusion of uric acid in the incubation medium during copper-induced low-density lipoprotein (LDL) oxidation exerted either an antioxidant or pro-oxidant effect. The pro-oxidant effect...
View articletitled, When and why a water-soluble antioxidant becomes pro-oxidant during copper-induced low-density lipoprotein oxidation: a study using uric acid
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Articles

Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins

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Linda J. HAZELL, Michael J. DAVIES, Roland STOCKER
Journal: Biochemical Journal
Biochem J (1999) 339 (3): 489–495.
https://doi.org/10.1042/bj3390489
Published: 26 April 1999
... by HOCl is a secondary reaction, with most HOCl consumed via rapid, non-radical reaction with apolipoprotein B-100. Subsequent incubation of HOCl-treated LDL gives rise to lipid peroxidation and antioxidant consumption in a time-dependent manner. Similarly, with myeloperoxidase/H 2 O 2 /Cl - (the source...
View articletitled, Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins
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