1-5 of 5
Keywords: arrestin
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Biochem J (2016) 473 (22): 4173–4192.
Published: 10 November 2016
... and kidney where it modulates extracellular Ca 2+ homeostasis and bone turnover. It is well established that phosphorylation of GPCRs constitutes a key event in regulating receptor function by promoting arrestin recruitment and coupling to G-protein-independent signaling pathways. Mapping phosphorylation...
Articles
Biochem J (2010) 428 (2): 235–245.
Published: 13 May 2010
...); β 2 AR is phosphorylated by both second messenger-activated PKA (protein kinase A) and GRKs with slower kinetics. TRHR co-internalizes with arrestin, whereas β 2 AR recruits arrestin, but internalizes without it. Both receptors are dephosphorylated following agonist removal, but TRHR...
Articles
Biochem J (2007) 408 (2): 221–230.
Published: 14 November 2007
...-arrestin-1-dependent inhibition of class IA PI3K (phosphoinositide 3-kinase), and we sought to characterize further the role of β-arrestins in the regulation of PI3K activity. Whereas the ability of β-arrestin-1 to inhibit p110α (PI3K catalytic subunit α) has been demonstrated, the role of β-arrestin-2...
Articles
Biochem J (2005) 385 (3): 625–637.
Published: 24 January 2005
... the concept of GPCR oligomerization, as well as demonstrating GPCR interactions with GPCR kinases, β-arrestins, adenylate cyclase and a subunit of an inwardly rectifying K + channel. The present review examines recent technological advances and experimental applications of FRET and BRET, discussing...
Articles
Biochem J (2003) 370 (1): 1–18.
Published: 15 February 2003
... over 16 isoforms, each of which is characterized by a unique N-terminal region. PDE4 isoforms play a pivotal role in controlling functionally and spatially distinct pools of cAMP by virtue of their unique intracellular targeting. Targeting occurs by association with proteins, such as arrestins, SRC...