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Keywords: aurora kinases
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Articles

Co-ordinated control of the Aurora B abscission checkpoint by PKCε complex assembly, midbody recruitment and retention

Lisa Watson, Tanya N. Soliman, Khalil Davis, Joanna Kelly, Nicola Lockwood, Xiaoping Yang, Steven Lynham, John D. Scott, Victoria Crossland, Neil Q. McDonald, David J. Mann, Alan Armstrong, Ulrike Eggert, Peter J. Parker
Journal: Biochemical Journal
Biochem J (2021) 478 (12): 2247–2263.
https://doi.org/10.1042/BCJ20210283
Published: 18 June 2021
... ) 14-3-3 abscission checkpoint aurora kinases midbody protein kinase C Checkpoints acting through the cell cycle serve as critical safeguards of genome integrity and determine the timing of progression. Amongst these is the Aurora B (S/T protein kinase) dependent abscission checkpoint...
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Includes: Supplementary data
Articles

The multifaceted allosteric regulation of Aurora kinase A

Nicholas Mark Levinson
Journal: Biochemical Journal
Biochem J (2018) 475 (12): 2025–2042.
https://doi.org/10.1042/BCJ20170771
Published: 26 June 2018
... 4.0 (CC BY-NC-ND) . Correspondence: Nicholas Mark Levinson ( [email protected] ) The mammalian Aurora kinases consist of a highly conserved C-terminal kinase domain and a much less conserved N-terminal domain of varying length ( Figure 1A ). The function of the N-terminal domain of AurA is still...
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