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Keywords: autoantibody
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Articles

Molecular structure of human GM-CSF in complex with a disease-associated anti-human GM-CSF autoantibody and its potential biological implications

Michaela Blech, Daniel Seeliger, Barbara Kistler, Margit M. T. Bauer, Mathias Hafner, Stefan Hörer, Markus Zeeb, Herbert Nar, John E. Park
Journal: Biochemical Journal
Biochem J (2012) 447 (2): 205–215.
https://doi.org/10.1042/BJ20120884
Published: 26 September 2012
...Michaela Blech; Daniel Seeliger; Barbara Kistler; Margit M. T. Bauer; Mathias Hafner; Stefan Hörer; Markus Zeeb; Herbert Nar; John E. Park Polyclonal autoantibodies against human GM-CSF (granulocyte/macrophage colony-stimulating factor) are a hallmark of PAP (pulmonary alveolar proteinosis...
View article titled, Molecular structure of human GM-CSF in complex with a disease-associated anti-human GM-CSF <span class="search-highlight">autoantibody</span> and its potential biological implications
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Includes: Supplementary data
Articles

Rescue of anaemia and autoimmune responses in SOD1 -deficient mice by transgenic expression of human SOD1 in erythrocytes

Yoshihito Iuchi, Futoshi Okada, Rina Takamiya, Noriko Kibe, Satoshi Tsunoda, Osamu Nakajima, Kazuyo Toyoda, Ritsuko Nagae, Makoto Suematsu, Tomoyoshi Soga, Koji Uchida, Junichi Fujii
Journal: Biochemical Journal
Biochem J (2009) 422 (2): 313–320.
https://doi.org/10.1042/BJ20090176
Published: 13 August 2009
...-SOD (superoxide dismutase)] gene deficiency causes anaemia, the production of autoantibodies against RBCs (red blood cells) and renal damage. In the present study, to further understand the role of oxidative stress in the autoimmune response triggered by SOD1 deficiency, we generated mice that had...
View article titled, Rescue of anaemia and autoimmune responses in SOD1 -deficient mice by transgenic expression of human SOD1 in erythrocytes
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Includes: Supplementary data
Articles

Elevated oxidative stress in erythrocytes due to a SOD1 deficiency causes anaemia and triggers autoantibody production

Yoshihito Iuchi, Futoshi Okada, Kunishige Onuma, Tadashi Onoda, Hironobu Asao, Masanobu Kobayashi, Junichi Fujii
Journal: Biochemical Journal
Biochem J (2007) 402 (2): 219–227.
https://doi.org/10.1042/BJ20061386
Published: 12 February 2007
... normally under conventional breeding conditions. In the present paper we report on a novel finding showing a distinct connection between oxidative stress in erythrocytes and the production of autoantibodies against erythrocytes in SOD1 −/− mice. Evidence is presented to show that SOD1 is primarily required...
View article titled, Elevated oxidative stress in erythrocytes due to a SOD1 deficiency causes anaemia and triggers <span class="search-highlight">autoantibody</span> production
Open the PDF for Elevated oxidative stress in erythrocytes due to a SOD1 deficiency causes anaemia and triggers <span class="search-highlight">autoantibody</span> production in another window
Includes: Supplementary data