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Keywords: beclin-1
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hVps15, but not Ca 2+ /CaM, is required for the activity and regulation of hVps34 in mammalian cells
Journal:
Biochemical Journal
Biochem J (2009) 417 (3): 747–755.
Published: 16 January 2009
... the activity and regulation of hVps34 expressed without or with hVps15. We find that hVps34 has low specific activity when expressed alone; co-expression with hVps15 leads to a marked increase in activity. Notably, beclin-1/UVRAG (UV radiation resistance-associated gene) activation of hVps34 requires co...