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Keywords: biased signalling
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Articles
Journal:
Biochemical Journal
Biochem J (2024) 481 (23): 1707–1722.
Published: 21 November 2024
... 24 10 2024 8 11 2024 © 2024 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2024 apelin receptor biased signalling conformational bias DRY G-protein-coupled receptors NPxxY GPCRs are the largest set of transmembrane (TM) proteins...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2015) 470 (2): 155–167.
Published: 20 August 2015
... which is known as biased signalling. The importance of biased signalling is that it may selectively activate biological responses to favour therapeutically beneficial signalling pathways and to avoid adverse effects. There are two levels of biased signalling. First, bias can arise from the ability...
