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Genome-wide identification and biochemical characterization of calcineurin B-like calcium sensor proteins in Chlamydomonas reinhardtii

Manoj Kumar, Komal Sharma, Akhilesh K. Yadav, Kajal Kanchan, Madhu Baghel, Suneel Kateriya, Girdhar K. Pandey

Biochem J (2020) 477 (10): 1879–1892.

https://doi.org/10.1042/BCJ20190960

Published: 28 May 2020

...Manoj Kumar; Komal Sharma; Akhilesh K. Yadav; Kajal Kanchan; Madhu Baghel; Suneel Kateriya; Girdhar K. Pandey Calcium (Ca 2+ ) signaling is involved in the regulation of diverse biological functions through association with several proteins that enable them to respond to abiotic and biotic stresses...

View article titled, Genome-wide identification and biochemical characterization of calcineurin B-like calcium sensor proteins in Chlamydomonas reinhardtii

Includes: Supplementary data

Articles

Calcium-induced dissociation of CIB1 from ASK1 regulates agonist-induced activation of the p38 MAPK pathway in platelets

Pravin Patel, Meghna U. Naik, Kalyan Golla, Noor F. Shaik, Ulhas P. Naik

Biochem J (2019) 476 (19): 2835–2850.

https://doi.org/10.1042/BCJ20190410

Published: 11 October 2019

...+ . Furthermore, treatment of platelets with thapsigargin or Ca 2+ ionophore robustly induced ASK1/p38 activation. In addition, calcium and integrin-binding protein 1 (CIB1), a Ca 2+ -dependent negative regulator of ASK1, associates with ASK1 in resting platelets and is dissociated upon platelet activation...

View article titled, Calcium-induced dissociation of CIB1 from ASK1 regulates agonist-induced activation of the p38 MAPK pathway in platelets

Includes: Supplementary data

Articles

Arabidopsis calcineurin B-like proteins differentially regulate phosphorylation activity of CBL-interacting protein kinase 9

Akhilesh K. Yadav, Saroj K. Jha, Sibaji K. Sanyal, Sheng Luan, Girdhar K. Pandey

Biochem J (2018) 475 (16): 2621–2636.

https://doi.org/10.1042/BCJ20180372

Published: 29 August 2018

...Akhilesh K. Yadav; Saroj K. Jha; Sibaji K. Sanyal; Sheng Luan; Girdhar K. Pandey Calcium (Ca 2+ ) is a versatile and ubiquitous second messenger in all eukaryotes including plants. In response to various stimuli, cytosolic calcium concentration ([Ca 2+ ] cyt ) is increased, leading to activation...

View article titled, Arabidopsis calcineurin B-like proteins differentially regulate phosphorylation activity of CBL-interacting protein kinase 9

Includes: Supplementary data

Articles

Effect of the actin- and calcium-regulating activities of ITPKB on the metastatic potential of lung cancer cells

Selina Bäder, Elina Glaubke, Saskia Grüb, Stefanie Muhs, Jasmin Wellbrock, Marcus Nalaskowski, Tobias Lange, Sabine Windhorst

Biochem J (2018) 475 (12): 2057–2071.

https://doi.org/10.1042/BCJ20180238

Published: 26 June 2018

...Selina Bäder; Elina Glaubke; Saskia Grüb; Stefanie Muhs; Jasmin Wellbrock; Marcus Nalaskowski; Tobias Lange; Sabine Windhorst Inositol-1,4,5-trisphosphate 3-kinase-A (ITPKA) exhibits oncogenic activity in lung cancer cells by regulating Ins(1,4,5)P 3 -mediated calcium release and cytoskeletal...

View article titled, Effect of the actin- and calcium-regulating activities of ITPKB on the metastatic potential of lung cancer cells

Includes: Supplementary data

Articles

Elevation of cytosolic Ca 2+ in response to energy deficiency in plants: the general mechanism of adaptation to low oxygen stress

Abir U. Igamberdiev, Robert D. Hill

Biochem J (2018) 475 (8): 1411–1425.

https://doi.org/10.1042/BCJ20180169

Published: 23 April 2018

...Abir U. Igamberdiev; Robert D. Hill Ca 2+ can be released from cell compartments to the cytosol during stress conditions. We discuss here the causes of Ca 2+ release under conditions of ATP concentration decline that result in the suppression of ATPases and activation of calcium ion channels...

View article titled, Elevation of cytosolic Ca 2+ in response to energy deficiency in plants: the general mechanism of adaptation to low oxygen stress

Articles

Functional characterization of the Ca 2+ -ATPase SMA1 from Schistosoma mansoni

Xavier Maréchal, Ricardo De Mendonça, Roger Miras, Jean Revilloud, Patrice Catty

Biochem J (2018) 475 (1): 289–303.

https://doi.org/10.1042/BCJ20170355

Published: 11 January 2018

... it in an active form in Saccharomyces cerevisiae , as previously done for SMA2. Using phosphorylation assays from ATP, we demonstrated that like SMA2, SMA1 bound calcium in a cooperative mode with an apparent affinity in the micromolar range. We also showed that SMA1 and SMA2 had close sensitivities...

View article titled, Functional characterization of the Ca 2+ -ATPase SMA1 from Schistosoma mansoni

Includes: Supplementary data

Articles

Vitamin D deficiency and diabetes

Michael J. Berridge

Biochem J (2017) 474 (8): 1321–1332.

https://doi.org/10.1042/BCJ20170042

Published: 24 March 2017

.... Correspondence: Michael J. Berridge ( [email protected] ) 13 1 2017 10 2 2017 13 2 2017 © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2017 calcium diabetes Vitamin D Diabetes, which is characterized...

View article titled, Vitamin D deficiency and diabetes

Articles

Dissecting the role of ADAM10 as a mediator of Staphylococcus aureus α-toxin action

Gisela von Hoven, Amable J. Rivas, Claudia Neukirch, Stefan Klein, Christian Hamm, Qianqian Qin, Martina Meyenburg, Sabine Füser, Paul Saftig, Nadja Hellmann, Rolf Postina, Matthias Husmann

Biochem J (2016) 473 (13): 1929–1940.

https://doi.org/10.1042/BCJ20160062

Published: 28 June 2016

... and metalloproteinase 10 (ADAM10) calcium cytotoxicity E-cadherin microtubule-associated protein 1A/1B light chain 3 (LC3) Staphylococcus aureus α-toxin α-Hemolysin or α-toxin, is the archetype of small β-pore-forming toxins [ 1 – 3 ] . It is a major exoproduct of Staphylococcus aureus , secreted...

View article titled, Dissecting the role of ADAM10 as a mediator of Staphylococcus aureus α-toxin action

Includes: Supplementary data

Articles

Quantification of active mitochondrial permeability transition pores using GNX-4975 inhibitor titrations provides insights into molecular identity

Andrew P. Richardson, Andrew P. Halestrap

Biochem J (2016) 473 (9): 1129–1140.

https://doi.org/10.1042/BCJ20160070

Published: 26 April 2016

... by factors that sensitize the MPTP to [Ca 2+ ]. We propose that GNX-4975 binds to this interface preventing a calcium-triggered event that opens the interface into a pore. 1 To whom correspondence should be addressed (email [email protected] ). 24 11 2015 19 2 2016 24 2 2016...

View article titled, Quantification of active mitochondrial permeability transition pores using GNX-4975 inhibitor titrations provides insights into molecular identity

Includes: Supplementary data

Articles

Cocaine inhibits store-operated Ca 2+ entry in brain microvascular endothelial cells: critical role for sigma-1 receptors

G. Cristina Brailoiu, Elena Deliu, Linda M. Console-Bram, Jonathan Soboloff, Mary E. Abood, Ellen M. Unterwald, Eugen Brailoiu

Biochem J (2016) 473 (1): 1–5.

https://doi.org/10.1042/BJ20150934

Published: 09 December 2015

... sigma-1 receptor-mediated inhibition of store-operated calcium entry (SOCE) in rat brain microvascular endothelial cells. Thus, we reveal sigma-1 receptors as SOCE blockers, adding novel insight regarding endothelial effects of cocaine and endogenous SOCE modulation. calcium calcium imaging...

View article titled, Cocaine inhibits store-operated Ca 2+ entry in brain microvascular endothelial cells: critical role for sigma-1 receptors

Articles

The activating role of phospho-(Tyr)-calmodulin on the epidermal growth factor receptor

Silviya R. Stateva, Valentina Salas, Alberto Benguría, Itziar Cossío, Estefanía Anguita, José Martín-Nieto, Gustavo Benaim, Antonio Villalobo

Biochem J (2015) 472 (2): 195–204.

https://doi.org/10.1042/BJ20150851

Published: 13 November 2015

... growth. calcium calmodulin epidermal growth factor receptor phospho-(Tyr)-calmodulin tyrosine kinase The sequential two-step phosphorylation assays were run continuously without any pause between each step. In the first step, the EGF-activated EGFR phosphorylated CaM and in the second...

View article titled, The activating role of phospho-(Tyr)-calmodulin on the epidermal growth factor receptor

Articles

Calcium modulation of exocytosis-linked plasma membrane potential oscillations in INS-1 832/13 cells

Akos A. Gerencser, Hindrik Mulder, David G. Nicholls

Biochem J (2015) 471 (1): 111–122.

https://doi.org/10.1042/BJ20150616

Published: 21 September 2015

... and prevalence. bioenergetics calcium exocytosis fluorescence membrane transport A key feature of glucose-stimulated insulin secretion in vivo is its pulsatile nature, with a typical periodicity of 2–5 min [ 1 ]. In fact, in Type 2 diabetes, which is largely caused by perturbed insulin...

View article titled, Calcium modulation of exocytosis-linked plasma membrane potential oscillations in INS-1 832/13 cells

Articles

The focal adhesion kinase Pyk2 links Ca 2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets

Ilaria Canobbio, Lina Cipolla, Gianni F. Guidetti, Daria Manganaro, Caterina Visconte, Soochong Kim, Mitsuhiko Okigaki, Marco Falasca, Satya P. Kunapuli, Mauro Torti

Biochem J (2015) 469 (2): 199–210.

https://doi.org/10.1042/BJ20150048

Published: 06 July 2015

... in the regulation of Ca 2+ -dependent protein-tyrosine phosphorylation. calcium G protein-coupled receptor (GPCR) platelets protein phosphorylation signal transduction tyrosine kinase thrombin The essential role of blood platelets in haemostasis and thrombosis relies on their ability...

View article titled, The focal adhesion kinase Pyk2 links Ca 2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets

Articles

Factor Xa dimerization competes with prothrombinase complex formation on platelet-like membrane surfaces

Tilen Koklic, Rima Chattopadhyay, Rinku Majumder, Barry R. Lentz

Biochem J (2015) 467 (1): 37–46.

https://doi.org/10.1042/BJ20141177

Published: 20 March 2015

.... This suggests a hitherto unanticipated mechanism by which PS-exposing platelet membranes can regulate amplification and propagation of blood coagulation. calcium coagulation dimerization factor Xa factor Va prothrombinase complex The platelet membrane is asymmetric in its lipid composition...

View article titled, Factor Xa dimerization competes with prothrombinase complex formation on platelet-like membrane surfaces

Includes: Supplementary data

Articles

TRPM2-mediated intracellular Zn 2+ release triggers pancreatic β-cell death

Paul T. Manna, Tim S. Munsey, Nada Abuarab, Fangfang Li, Aruna Asipu, Gareth Howell, Alicia Sedo, Wei Yang, Jacqui Naylor, David J. Beech, Lin-Hua Jiang, Asipu Sivaprasadarao

Biochem J (2015) 466 (3): 537–546.

https://doi.org/10.1042/BJ20140747

Published: 06 March 2015

... taken with an LSM 510 inverted confocal microscope using a 40× oil-immersion objective. apoptosis calcium reactive oxygen species Type 1 diabetes transient receptor potential (melastatin) 2 (TRPM2) channels zinc Human embryonic kidney (HEK)-293 and insulin secreting (INS1) cells were...

View article titled, TRPM2-mediated intracellular Zn 2+ release triggers pancreatic β-cell death

Includes: Supplementary data

Articles

The proteins of exocytosis: lessons from the sperm model

Claudia Nora Tomes

Biochem J (2015) 465 (3): 359–370.

https://doi.org/10.1042/BJ20141169

Published: 22 January 2015

...Claudia Nora Tomes Exocytosis is a highly regulated process that consists of multiple functionally, kinetically and/or morphologically definable stages such as recruitment, targeting, tethering and docking of secretory vesicles with the plasma membrane, priming of the fusion machinery and calcium...

View article titled, The proteins of exocytosis: lessons from the sperm model

Articles

Calcium/Ask1/MKK7/JNK2/c-Src signalling cascade mediates disruption of intestinal epithelial tight junctions by dextran sulfate sodium

Geetha Samak, Kamaljit K. Chaudhry, Ruchika Gangwar, Damodaran Narayanan, Jonathan H. Jaggar, RadhaKrishna Rao

Biochem J (2015) 465 (3): 503–515.

https://doi.org/10.1042/BJ20140450

Published: 22 January 2015

... disruption and barrier dysfunction using Caco-2 cell monolayers and mouse intestine. We further investigated the importance of intracellular calcium ([Ca 2+ ] i ) in DSS-induced JNK2 activation, the JNK-mediated c-Src activation and c-Src-mediated tyrosine phosphorylation of tight junction and adherens...

View article titled, Calcium/Ask1/MKK7/JNK2/c-Src signalling cascade mediates disruption of intestinal epithelial tight junctions by dextran sulfate sodium

Includes: Supplementary data

Articles

Eukaryotic elongation factor 2 kinase regulates the cold stress response by slowing translation elongation

John R. P. Knight, Amandine Bastide, Anne Roobol, Jo Roobol, Thomas J. Jackson, Wahyu Utami, David A. Barrett, C. Mark Smales, Anne E. Willis

Biochem J (2015) 465 (2): 227–238.

https://doi.org/10.1042/BJ20141014

Published: 06 January 2015

... (eukaryotic elongation factor 2 kinase). calcium cold-shock eukaryotic elongation factor 2 (eEF2) eukaryotic elongation factor 2 kinase (eEF2K) hypothermia protein synthesis The control of protein synthesis is an essential component of the response to deviation from an ambient environment...

View article titled, Eukaryotic elongation factor 2 kinase regulates the cold stress response by slowing translation elongation

Includes: Supplementary data

Articles

Ca 2+ switches the effect of PS-containing membranes on Factor Xa from activating to inhibiting: implications for initiation of blood coagulation

Tilen Koklic, Rinku Majumder, Barry R. Lentz

Biochem J (2014) 462 (3): 591–601.

https://doi.org/10.1042/BJ20140130

Published: 22 August 2014

...Tilen Koklic; Rinku Majumder; Barry R. Lentz Calcium (Ca 2+ ) plays a pivotal role in cellular and organismal physiology. The Ca 2+ ion has an intermediate protein-binding affinity and thus it can serve as an on/off switch in the regulation of different biochemical processes. The serum level...

View article titled, Ca 2+ switches the effect of PS-containing membranes on Factor Xa from activating to inhibiting: implications for initiation of blood coagulation

Articles

Amyloid β-peptide-dependent activation of human platelets: essential role for Ca 2+ and ADP in aggregation and thrombus formation

Ilaria Canobbio, Gianni F. Guidetti, Barbara Oliviero, Daria Manganaro, Dina Vara, Mauro Torti, Giordano Pula

Biochem J (2014) 462 (3): 513–523.

https://doi.org/10.1042/BJ20140307

Published: 22 August 2014

... the cerebrovascular component of Alzheimer's disease. ADP Alzheimer’s disease (AD) calcium platelet secretion thrombosis 6 3 2014 23 6 2014 1 7 2014 1 7 2014 © The Authors Journal compilation © 2014 Biochemical Society 2014 We demonstrate that the amyloid β-peptide...

View article titled, Amyloid β-peptide-dependent activation of human platelets: essential role for Ca 2+ and ADP in aggregation and thrombus formation

Includes: Supplementary data

Articles

The N-terminal region of two-pore channel 1 regulates trafficking and activation by NAADP

Dev Churamani, Robert Hooper, Taufiq Rahman, Eugen Brailoiu, Sandip Patel

Biochem J (2013) 453 (1): 147–151.

https://doi.org/10.1042/BJ20130474

Published: 13 June 2013

... These authors contributed equally to this work. 2 To whom correspondence should be addressed (email [email protected] ). 12 4 2013 1 5 2013 2 5 2013 2 5 2013 © The Authors Journal compilation © 2013 Biochemical Society 2013 calcium endosome lysosome nicotinic acid...

View article titled, The N-terminal region of two-pore channel 1 regulates trafficking and activation by NAADP

Articles

Inhibition of Plasmodium falciparum CDPK1 by conditional expression of its J-domain demonstrates a key role in schizont development

Mauro F. Azevedo, Paul R. Sanders, Efrosinia Krejany, Catherine Q. Nie, Ping Fu, Leon A. Bach, Gerhard Wunderlich, Brendan S. Crabb, Paul R. Gilson

Biochem J (2013) 452 (3): 433–441.

https://doi.org/10.1042/BJ20130124

Published: 31 May 2013

...Mauro F. Azevedo; Paul R. Sanders; Efrosinia Krejany; Catherine Q. Nie; Ping Fu; Leon A. Bach; Gerhard Wunderlich; Brendan S. Crabb; Paul R. Gilson PfCDPK1 [ Plasmodium falciparum CDPK1 (calcium-dependent protein kinase 1)] is highly expressed in parasite asexual blood and mosquito stages. Its role...

View article titled, Inhibition of Plasmodium falciparum CDPK1 by conditional expression of its J-domain demonstrates a key role in schizont development

Includes: Supplementary data

Articles

Extracellular calcium influx activates adenylate cyclase 1 and potentiates insulin secretion in MIN6 cells

Tetsuya Kitaguchi, Manami Oya, Yoshiko Wada, Takashi Tsuboi, Atsushi Miyawaki

Biochem J (2013) 450 (2): 365–373.

https://doi.org/10.1042/BJ20121022

Published: 15 February 2013

... 2013 Biochemical Society 2013 calcium cAMP exchange protein directly activated by cAMP 1 (Epac1) exocytosis fluorescence microscopy insulin total internal reflection yellow fluorescent protein Flamindo in the pRSET B vector was transformed into Escherichia coli JM109 (DE3) cells...

View article titled, Extracellular calcium influx activates adenylate cyclase 1 and potentiates insulin secretion in MIN6 cells

Includes: Supplementary data

Articles

Generation and characterization of a lysosomally targeted, genetically encoded Ca 2+ -sensor

Hannah V. McCue, Joanna D. Wardyn, Robert D. Burgoyne, Lee P. Haynes

Biochem J (2013) 449 (2): 449–457.

https://doi.org/10.1042/BJ20120898

Published: 14 December 2012

... is properly cited. cameleon calcium fluorescence resonance energy transfer (FRET) lysosome sensor signalling targeting Ca 2+ signalling is ubiquitous within animal cells and has an impact upon all aspects of normal cellular physiology to some degree [ 1 , 2 ]. The utility of the Ca 2...

View article titled, Generation and characterization of a lysosomally targeted, genetically encoded Ca 2+ -sensor

Includes: Multimedia, Supplementary data

Articles

Activation of PLC by an endogenous cytokine (GBP) in Drosophila S3 cells and its application as a model for studying inositol phosphate signalling through ITPK1

Yixing Zhou, Shilan Wu, Huanchen Wang, Yoichi Hayakawa, Gary S. Bird, Stephen B. Shears

Biochem J (2012) 448 (2): 273–283.

https://doi.org/10.1042/BJ20120730

Published: 07 November 2012

..., and F is the measured fluorescence intensity. 1 To whom correspondence should be addressed (email [email protected] ). 30 4 2012 21 8 2012 29 8 2012 29 8 2012 © The Authors Journal compilation © 2012 Biochemical Society 2012 calcium Drosophila...

View article titled, Activation of PLC by an endogenous cytokine (GBP) in Drosophila S3 cells and its application as a model for studying inositol phosphate signalling through ITPK1

Includes: Supplementary data

Articles

2-APB-potentiated channels amplify CatSper-induced Ca 2+ signals in human sperm

Linda Lefièvre, Katherine Nash, Steven Mansell, Sarah Costello, Emma Punt, Joao Correia, Jennifer Morris, Jackson Kirkman-Brown, Stuart M. Wilson, Christopher L. R. Barratt, Stephen Publicover

Biochem J (2012) 448 (2): 189–200.

https://doi.org/10.1042/BJ20120339

Published: 07 November 2012

... permits unrestricted non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited. calcium CatSper hyperactivation progesterone sperm store-operated channel The amplitude of the progesterone-induced [Ca 2+ ] i transient was calculated...

View article titled, 2-APB-potentiated channels amplify CatSper-induced Ca 2+ signals in human sperm

Includes: Multimedia, Supplementary data

Articles

Involvement of TSSA (trypomastigote small surface antigen) in Trypanosoma cruzi invasion of mammalian cells

Gaspar E. Cánepa, Maria Sol Degese, Alexandre Budu, Celia R. S. Garcia, Carlos A. Buscaglia

Biochem J (2012) 444 (2): 211–218.

https://doi.org/10.1042/BJ20120074

Published: 11 May 2012

...) Abs were purified from the serum of a GST–TSSA-VI-immunized rabbit [ 21 ] by affinity chromatography [ 23 ]. 10 1 2012 15 3 2012 20 3 2012 20 3 2012 © The Authors Journal compilation © 2012 Biochemical Society 2012 calcium cell invasion mucin Trypanosoma cruzi...

View article titled, Involvement of TSSA (trypomastigote small surface antigen) in Trypanosoma cruzi invasion of mammalian cells

Includes: Supplementary data

Articles

Heat-shock proteins attenuate SERCA inactivation by the anti-apoptotic protein Bcl-2: possible implications for the ER Ca 2+ -mediated apoptosis

Elena S. Dremina, Victor S. Sharov, Christian Schöneich

Biochem J (2012) 444 (1): 127–139.

https://doi.org/10.1042/BJ20111114

Published: 26 April 2012

.... 1 To whom correspondence should be addressed (email [email protected] ). 22 6 2011 16 1 2012 23 2 2012 23 2 2012 © The Authors Journal compilation © 2012 Biochemical Society 2012 apoptosis Bcl-2 calcium endoplasmic reticulum heat-shock protein sarcoplasmic...

View article titled, Heat-shock proteins attenuate SERCA inactivation by the anti-apoptotic protein Bcl-2: possible implications for the ER Ca 2+ -mediated apoptosis

Articles

Glu 106 in the Orai1 pore contributes to fast Ca 2+ -dependent inactivation and pH dependence of Ca 2+ release-activated Ca 2+ (CRAC) current

Nathan R. Scrimgeour, David P. Wilson, Grigori Y. Rychkov

Biochem J (2012) 441 (2): 743–753.

https://doi.org/10.1042/BJ20110558

Published: 21 December 2011

... suggest that Glu 106 inside the CRAC channel pore is involved in co-ordinating the Ca 2+ -binding site that mediates fast Ca 2+ -dependent inactivation. calcium Ca 2+ release-activated Ca 2+ current ( I CRAC ) gating patch clamp pH dependence (1) Where P min is an offset, V...

View article titled, Glu 106 in the Orai1 pore contributes to fast Ca 2+ -dependent inactivation and pH dependence of Ca 2+ release-activated Ca 2+ (CRAC) current

Includes: Supplementary data

Articles

NAADP regulates human platelet function

Carmen H. Coxon, Alexander M. Lewis, Amanda J. Sadler, Sridhar R. Vasudevan, Andrew Thomas, Kirsten A. Dundas, Lewis Taylor, R. Duncan Campbell, Jonathan M. Gibbins, Grant C. Churchill, Katherine L. Tucker

Biochem J (2012) 441 (1): 435–442.

https://doi.org/10.1042/BJ20111175

Published: 14 December 2011

... this time, agonist was added and stirring was initiated. Aggregations were followed for 5 min following the addition of agonist. © The Authors Journal compilation © 2012 Biochemical Society 2012 calcium cell signalling Ned-19 nicotinamide acid–adenine dinucleotide phosphate (NAADP) platelet...

View article titled, NAADP regulates human platelet function

Articles

Divergent effect of mammalian PLCζ in generating Ca 2+ oscillations in somatic cells compared with eggs

Sally V. Phillips, Yuansong Yu, Andreas Rossbach, Michail Nomikos, Vyronia Vassilakopoulou, Evangelia Livaniou, Bevan Cumbes, F. Anthony Lai, Christopher H. George, Karl Swann

Biochem J (2011) 438 (3): 545–553.

https://doi.org/10.1042/BJ20101581

Published: 26 August 2011

... and reproduction in any medium, provided the original work is properly cited. calcium Chinese-hamster ovary (CHO) cell egg oscillation phospholipase C (PLC) sperm PLCζ (phospholipase Cζ) is an isoform of phosphoinositide-specific PLC that is specifically expressed in mammalian sperm cells [ 1...

View article titled, Divergent effect of mammalian PLCζ in generating Ca 2+ oscillations in somatic cells compared with eggs

Includes: Supplementary data

Articles

Molecular interaction and functional regulation of connexin50 gap junctions by calmodulin

Yanyi Chen, Yubin Zhou, Xianming Lin, Hing-Cheung Wong, Qin Xu, Jie Jiang, Siming Wang, Monica M. Lurtz, Charles F. Louis, Richard D. Veenstra, Jenny J. Yang

Biochem J (2011) 435 (3): 711–722.

https://doi.org/10.1042/BJ20101726

Published: 13 April 2011

... 2011 14 2 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 calcium calmodulin connexin50 gap junction junctional conductance protein–protein interaction The circulation of current fluid flow through the closely packed cells of the lens of the eye...

View article titled, Molecular interaction and functional regulation of connexin50 gap junctions by calmodulin

Includes: Supplementary data

Articles

The C2 domain of Tollip, a Toll-like receptor signalling regulator, exhibits broad preference for phosphoinositides

Gayatri Ankem, Sharmistha Mitra, Furong Sun, Anna C. Moreno, Boonta Chutvirasakul, Hugo F. Azurmendi, Liwu Li, Daniel G. S. Capelluto

Biochem J (2011) 435 (3): 597–608.

https://doi.org/10.1042/BJ20102160

Published: 13 April 2011

..., which promotes pro-inflammatory responses by mediating cytokine gene expression [ 5 ]. C2 domain calcium nuclear magnetic resonance (NMR) phosphoinositide Toll-interacting protein (Tollip) Toll-like receptor (TLR) © The Authors Journal compilation © 2011 Biochemical Society 2011...

View article titled, The C2 domain of Tollip, a Toll-like receptor signalling regulator, exhibits broad preference for phosphoinositides

Includes: Supplementary data

Articles

Similarities and differences in the structure and function of 4.1G and 4.1R 135 , two protein 4.1 paralogues expressed in erythroid cells

Wataru Nunomura, Kengo Kinoshita, Marilyn Parra, Philippe Gascard, Xiuli An, Narla Mohandas, Yuichi Takakuwa

Biochem J (2010) 432 (2): 407–416.

https://doi.org/10.1042/BJ20100041

Published: 12 November 2010

.... In the present study, we performed detailed characterization of the interaction of 4.1G with various erythroid membrane proteins and the regulation of these interactions by calcium-saturated calmodulin. Like both isoforms of 4.1R, 4.1G bound to band 3, glycophorin C, CD44, p55 and calmodulin. While both 4.1G...

View article titled, Similarities and differences in the structure and function of 4.1G and 4.1R 135 , two protein 4.1 paralogues expressed in erythroid cells

Includes: Supplementary data

Articles

Evidence for an interaction between Golli and STIM1 in store-operated calcium entry

Ciara M. Walsh, Mary K. Doherty, Alexei V. Tepikin, Robert D. Burgoyne

Biochem J (2010) 430 (3): 453–460.

https://doi.org/10.1042/BJ20100650

Published: 27 August 2010

..., provided the original work is properly cited. calcium endoplasmic reticulum (ER) Golli myelin basic protein (MBP) store-operated Ca 2+ entry (SOCE) stromal interaction molecule 1 (STIM1) A previous paper by Varnai et al. [ 21 ] suggested that STIM1 and Orai1 form part of a large...

View article titled, Evidence for an interaction between Golli and STIM1 in store-operated calcium entry

Articles

Calcium- and polyphosphate-containing acidic granules of sea urchin eggs are similar to acidocalcisomes, but are not the targets for NAADP

Isabela B. Ramos, Kildare Miranda, Douglas A. Pace, Katherine C. Verbist, Fu-Yang Lin, Yonghui Zhang, Eric Oldfield, Ednildo A. Machado, Wanderley De Souza, Roberto Docampo

Biochem J (2010) 429 (3): 485–495.

https://doi.org/10.1042/BJ20091956

Published: 14 July 2010

...Isabela B. Ramos; Kildare Miranda; Douglas A. Pace; Katherine C. Verbist; Fu-Yang Lin; Yonghui Zhang; Eric Oldfield; Ednildo A. Machado; Wanderley De Souza; Roberto Docampo Acidocalcisomes are acidic calcium-storage compartments described from bacteria to humans and characterized by their high...

View article titled, Calcium- and polyphosphate-containing acidic granules of sea urchin eggs are similar to acidocalcisomes, but are not the targets for NAADP

Includes: Multimedia, Supplementary data

Articles

The arginylation-dependent association of calreticulin with stress granules is regulated by calcium

Marcos A. Carpio, Cecilia López Sambrooks, Edith S. Durand, Marta E. Hallak

Biochem J (2010) 429 (1): 63–72.

https://doi.org/10.1042/BJ20091953

Published: 14 June 2010

... calreticulin calcium post-translational modification retrotranslocation stress granule Cell lines were grown to 90% confluence, washed twice with PBS and disrupted in a lysis buffer as described in Decca et al. [ 12 ]. The TIA-1 component of SGs was immunoprecipitated using an anti-(TIA-1...

View article titled, The arginylation-dependent association of calreticulin with stress granules is regulated by calcium

Articles

The vasoactive peptides urotensin II and urotensin II-related peptide regulate astrocyte activity through common and distinct mechanisms: involvement in cell proliferation

Marie Jarry, Mickaël Diallo, Céline Lecointre, Laurence Desrues, Tursonjan Tokay, David Chatenet, Jérôme Leprince, Oriana Rossi, Hubert Vaudry, Marie-Christine Tonon, Laurent Prézeau, Hélène Castel, Pierrick Gandolfo

Biochem J (2010) 428 (1): 113–124.

https://doi.org/10.1042/BJ20090867

Published: 28 April 2010

.... astrocyte bioluminescence resonance energy transfer calcium cell proliferation G-protein urotensin II receptor Astrocytes (5 DIV) were incubated for 60 min at 37 °C with fresh serum-free medium in the absence or presence of test substances. Peptides contained in culture medium were concentrated...

View article titled, The vasoactive peptides urotensin II and urotensin II-related peptide regulate astrocyte activity through common and distinct mechanisms: involvement in cell proliferation

Articles

Calcineurin/Crz1 destabilizes Msn2 and Msn4 in the nucleus in response to Ca 2+ in Saccharomyces cerevisiae

Yoshifumi Takatsume, Takumi Ohdate, Kazuhiro Maeta, Wataru Nomura, Shingo Izawa, Yoshiharu Inoue

Biochem J (2010) 427 (2): 275–287.

https://doi.org/10.1042/BJ20091334

Published: 29 March 2010

... [email protected] ). 26 8 2009 4 1 2010 2 2 2010 2 2 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 calcineurin calcium Crz1 FK506 methylglyoxal Msn2/Msn4 MG (methylglyoxal) is a typical 2-oxoaldehyde that is synthesized...

View article titled, Calcineurin/Crz1 destabilizes Msn2 and Msn4 in the nucleus in response to Ca 2+ in Saccharomyces cerevisiae

Includes: Supplementary data

Articles

Functional interaction between Smad3 and S100A4 (metastatin-1) for TGF-β-mediated cancer cell invasiveness

Isao Matsuura, Chen-Yu Lai, Keng-Nan Chiang

Biochem J (2010) 426 (3): 327–335.

https://doi.org/10.1042/BJ20090990

Published: 24 February 2010

... 2010 13 1 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 calcium matrix metalloproteinase-9 (MMP-9) metastasis S100A4 Smad3 transforming growth factor-β (TGF-β) For the mammalian two-hybrid assay, HEK-293T cells on a 12-well plate were transfected...

View article titled, Functional interaction between Smad3 and S100A4 (metastatin-1) for TGF-β-mediated cancer cell invasiveness

Articles

Breaking the code: Ca 2+ sensors in plant signalling

Thomas A. DeFalco, Kyle W. Bender, Wayne A. Snedden

Biochem J (2010) 425 (1): 27–40.

https://doi.org/10.1042/BJ20091147

Published: 14 December 2009

...-hand Ca 2+ sensors in plants are CaMs [calmodulins; including CMLs (CaM-like proteins)], CDPKs (calcium-dependent protein kinases) and CBLs (calcineurin B-like proteins). In the plant species examined to date, each of these classes is represented by a large family of proteins, most of which have...

View article titled, Breaking the code: Ca 2+ sensors in plant signalling

Articles

Asporin competes with decorin for collagen binding, binds calcium and promotes osteoblast collagen mineralization

Sebastian Kalamajski, Anders Aspberg, Karin Lindblom, Dick Heinegård, Åke Oldberg

Biochem J (2009) 423 (1): 53–59.

https://doi.org/10.1042/BJ20090542

Published: 14 September 2009

... asporin fragment LRR (leucine-rich repeat) 10–12 and by full-length decorin, but not by biglycan. We demonstrate that the polyaspartate domain binds calcium and regulates hydroxyapatite formation in vitro . In the presence of asporin, the number of collagen nodules, and mRNA of osteoblastic markers...

View article titled, Asporin competes with decorin for collagen binding, binds calcium and promotes osteoblast collagen mineralization

Includes: Supplementary data

Articles

Differential contributions of Glu 96 , Asp 102 and Asp 111 to coagulation Factor V/Va metal ion binding and subunit stability

Jina Song, Kimberley Talbot, Jeffrey Hewitt, Ross T. A. MacGillivray, Edward L. G. Pryzdial

Biochem J (2009) 422 (2): 257–264.

https://doi.org/10.1042/BJ20090405

Published: 13 August 2009

..., possibly at the metal ion-dependent subunit interface. 1 To whom correspondence should be addressed (email [email protected] ). 9 3 2009 6 5 2009 12 6 2009 12 6 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 B domain calcium coagulation...

View article titled, Differential contributions of Glu 96 , Asp 102 and Asp 111 to coagulation Factor V/Va metal ion binding and subunit stability

Articles

NAADP-mediated channel ‘chatter’ in neurons of the rat medulla oblongata

G. Cristina Brailoiu, Eugen Brailoiu, Raman Parkesh, Antony Galione, Grant C. Churchill, Sandip Patel, Nae J. Dun

Biochem J (2009) 419 (1): 91–99.

https://doi.org/10.1042/BJ20081138

Published: 13 March 2009

... (pH 7.2) with or without IP 3 (10 μM). © The Authors Journal compilation © 2009 Biochemical Society 2009 calcium nicotinic acid–adenine dinucleotide phosphate (NAADP) non-selective cation channel patch-clamp Visual patch-clamp recordings were made from neurons of nucleus...

View article titled, NAADP-mediated channel ‘chatter’ in neurons of the rat medulla oblongata

Includes: Supplementary data

Articles

Extracellular Ca 2+ transients affect poly-( R )-3-hydroxybutyrate regulation by the AtoS-AtoC system in Escherichia coli

Marina C. Theodorou, Ekaterini Tiligada, Dimitrios A. Kyriakidis

Biochem J (2009) 417 (3): 667–672.

https://doi.org/10.1042/BJ20081169

Published: 16 January 2009

... Biochemical Society 2009 AtoS-AtoC two-component system atoDAEB calcium calcium channel blocker histamine poly-(R)-3-hydroxybutyrate Ca 2+ is implicated in the regulation of a wide variety of cellular processes, including signal transduction in bacteria, where cytosolic Ca 2+ levels...

View article titled, Extracellular Ca 2+ transients affect poly-( R )-3-hydroxybutyrate regulation by the AtoS-AtoC system in Escherichia coli

Articles

Protective effect of paraoxonase-2 against endoplasmic reticulum stress-induced apoptosis is lost upon disturbance of calcium homoeostasis

Sven Horke, Ines Witte, Petra Wilgenbus, Sebastian Altenhöfer, Maximilian Krüger, Huige Li, Ulrich Förstermann

Biochem J (2008) 416 (3): 395–405.

https://doi.org/10.1042/BJ20080775

Published: 26 November 2008

... the efficacy of putative cellular defence mechanisms. 1 To whom correspondence should be addressed (email [email protected] ). 14 4 2008 8 8 2008 11 8 2008 11 8 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 apoptosis calcium calpain...

View article titled, Protective effect of paraoxonase-2 against endoplasmic reticulum stress-induced apoptosis is lost upon disturbance of calcium homoeostasis

Articles

Tyrosine modification enhances metal-ion binding

Graham S. Baldwin, Michael F. Bailey, B. Philip Shehan, Ioulia Sims, Raymond S. Norton

Biochem J (2008) 416 (1): 77–84.

https://doi.org/10.1042/BJ20081059

Published: 28 October 2008

... was then aspirated, and the cells were washed once with PBS and dissolved in 0.25 M NaOH (300 μl/well). Radioactivity in the resulting solution was measured in a gamma-counter (LKB Wallac). calcium cholecystokinin ferric ion iron phosphotyrosine sulfotyrosine Modification of tyrosine residues...

View article titled, Tyrosine modification enhances metal-ion binding

Includes: Supplementary data

Articles

Structure–function analysis of plant aquaporin At PIP2;1 gating by divalent cations and protons

Lionel Verdoucq, Alexandre Grondin, Christophe Maurel

Biochem J (2008) 415 (3): 409–416.

https://doi.org/10.1042/BJ20080275

Published: 15 October 2008

... and manganese were identified, in addition to calcium (Ca 2+ ) and H + as potent inhibitors of WT At PIP2;1. Our results further show that His 199 , the previously identified site for H + sensing, but also N-terminal located Glu 31 , and to a lesser extent Asp 28 , are involved in both divalent-cation- and H...

View article titled, Structure–function analysis of plant aquaporin At PIP2;1 gating by divalent cations and protons

Articles

Increasing the expression of calcium-permeable TRPC3 and TRPC7 channels enhances constitutive secretion

Verna Lavender, Setareh Chong, Katherine Ralphs, Adrian J. Wolstenholme, Barbara J. Reaves

Biochem J (2008) 413 (3): 437–446.

https://doi.org/10.1042/BJ20071488

Published: 15 July 2008

...Verna Lavender; Setareh Chong; Katherine Ralphs; Adrian J. Wolstenholme; Barbara J. Reaves The hTRPC [human TRPC (canonical transient receptor potential)] family of non-selective cation channels is proposed to mediate calcium influx across the plasma membrane via PLC (phospholipase C)-coupled...

View article titled, Increasing the expression of calcium-permeable TRPC3 and TRPC7 channels enhances constitutive secretion

Articles

Specific effects of KChIP3/calsenilin/DREAM, but not KChIPs 1, 2 and 4, on calcium signalling and regulated secretion in PC12 cells

Neil Venn, Lee P. Haynes, Robert D. Burgoyne

Biochem J (2008) 413 (1): 71–80.

https://doi.org/10.1042/BJ20080441

Published: 12 June 2008

...Neil Venn; Lee P. Haynes; Robert D. Burgoyne The KChIPs (K + channel-interacting proteins) are members of the NCS (neuronal calcium sensor) protein family of Ca 2+ -binding proteins. It is unclear to what extent the KChIPs have distinct functions although they all interact with Kv4 K + channels...

View article titled, Specific effects of KChIP3/calsenilin/DREAM, but not KChIPs 1, 2 and 4, on calcium signalling and regulated secretion in PC12 cells

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