...Rainer Kalscheuer; Ainhoa Palacios; Itxaso Anso; Javier Cifuente; Juan Anguita; William R. Jacobs, Jr; Marcelo E. Guerin; Rafael Prados-Rosales Bacterial capsules have evolved to be at the forefront of the cell envelope, making them an essential element of bacterial biology. Efforts to understand...

... Cryptococcus neoformans . In this fungus, UDP-GlcA is required for the synthesis of capsule polysaccharides, which in turn are essential for virulence. The gene was expressed in Escherichia coli and the 51.3-kDa recombinant protein from wild-type and five mutants was purified for analysis. The cryptococcal...