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Keywords: carboxypeptidase E
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Articles

Membrane-bound carboxypeptidase E facilitates the entry of eosinophil cationic protein into neuroendocrine cells

Chia-Mao WU, Hao-Teng CHANG, Margaret Dah-Tsyr CHANG
Journal: Biochemical Journal
Biochem J (2004) 382 (3): 841–848.
https://doi.org/10.1042/BJ20040894
Published: 07 September 2004
... found that mECP–eGFP–6H entered into GH3 neuroendocrine cells and inhibited the growth of the cells with an IC 50 of 0.8 μM. By yeast two-hybrid screening and immunoprecipitation, we have identified a specific protein–protein interaction between mECP and CPE (carboxypeptidase E), a well characterized...
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Articles

Sorting of carboxypeptidase E to the regulated secretory pathway requires interaction of its transmembrane domain with lipid rafts

Chun-Fa ZHANG, Savita DHANVANTARI, Hong LOU, Y. Peng LOH
Journal: Biochemical Journal
Biochem J (2003) 369 (3): 453–460.
https://doi.org/10.1042/bj20020827
Published: 01 February 2003
...Chun-Fa ZHANG; Savita DHANVANTARI; Hong LOU; Y. Peng LOH Carboxypeptidase E (CPE) functions as a regulated secretory pathway sorting receptor for several prohormones, including pro-opiomelanocortin (POMC), proenkephalin and proinsulin. The association of CPE with lipid rafts in the trans -Golgi...
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