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Keywords: carcinogenesis
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Articles
Biochem J (2017) 474 (17): 3011–3025.
Published: 22 August 2017
... studying the cellular, biochemical and molecular changes associated with oral carcinogenesis. The present study aims to deal with the above need using Acacia nilotica (L.) leaf extract (AN) and ethyl gallate (EG), a phenolic compound present in AN against oral carcinogenesis. Extension of a tumor cell line...
Articles
Biochem J (2012) 442 (2): 311–321.
Published: 13 February 2012
... miR-17 plays an important role in CRC carcinogenesis by targeting RND3 and may be a therapeutic agent for CRC. 1 Correspondence may be addressed to either of these authors (email wudehua.gd@gmail.com or liliu.gd@gmail.com ). © The Authors Journal compilation © 2012 Biochemical Society...
Includes: Supplementary data
Articles
Biochem J (2011) 439 (1): 113–128.
Published: 14 September 2011
... remaining allele were detected [ 10 ]. Therefore any direct evidence that disruption of one DIRC2 allele was a causative element during carcinogenesis in these patients is so far missing. Analysis of the DIRC2 expression pattern at the mRNA level has revealed ubiquitous expression with slightly higher...
Includes: Supplementary data
Articles
Biochem J (2005) 388 (3): 813–818.
Published: 07 June 2005
...Ayako FURUKAWA; Yusuke HIRAKU; Shinji OIKAWA; Catherine LUXFORD; Michael J. DAVIES; Shosuke KAWANISHI In γ-irradiation, • OH is directly generated from water and causes DNA damage leading to carcinogenesis. Exposure of proteins to γ-irradiation, in the presence of oxygen, gives high yields of...
Articles
Biochem J (2005) 386 (1): 35–45.
Published: 08 February 2005
... participate in pancreatic carcinogenesis. Our aim was to investigate in parallel the role of the Ets factor PEA3 in MUC4 and ErbB-2 transcriptional regulation in pancreatic cancer cells. Two MUC4 -expressing WD (well-differentiated) (CAPAN-1 and -2) and one MUC4 -non-expressing poorly differentiated (PANC-1...
Articles
Biochem J (2002) 365 (2): 405–416.
Published: 15 July 2002
... DDBJ, EMBL, GenBank ® and GSDB Nucleotide Sequence Databases under the accession number AF501320. 25 2 2002 16 4 2002 3 5 2002 The Biochemical Society, London ©2002 2002 antioxidant responsive element cancer chemoprevention carcinogenesis detoxification glutamate...
Articles
Biochem J (2001) 357 (2): 489–495.
Published: 09 July 2001
... carcinogenesis keratinocytes ornithine decarboxylase Abbreviations used: ODC, ornithine decarboxylase; DFMO, α-difluoromethylornithine; MAP, mitogen-activated protein; MEK1, MAP kinase kinase 1. Biochem. J. (2001) 357, 489 495 (Printed in Great Britain) 489 Polyamines regulate gap junction...
Articles
Biochem J (2000) 348 (3): 497–506.
Published: 07 June 2000
... potencies of carcinogens. 1 To whom correspondence should be addressed (e-mail rasnick@mindspring.com). 25 11 1999 6 3 2000 10 4 2000 The Biochemical Society, London © 2000 2000 carcinogenesis dynamics metabolic control analysis Biochem. J. (2000) 348, 497 506...
Articles
Biochem J (1999) 340 (3): 621–630.
Published: 08 June 1999
... tetraploidization followed by a gradual loss of chromosomes. Thus the initiation step of carcinogenesis produces aneuploidy below the threshold for cancer, and the promotion step increases the level of aneuploidy above this threshold. We conclude that aneuploidy offers a simple and coherent explanation for all the...
Articles
Biochem J (1999) 338 (2): 489–498.
Published: 22 February 1999
... work suggests that these enzymes play a protective role in chemical carcinogenesis [Strassburg, Manns and Tukey (1997) Cancer Res. 57 , 2979–2985]. In this study, UGT1 and UGT2 gene expression was investigated in human oesophageal epithelium and squamous-cell carcinoma in addition to the...