...Salvador González-Gordo; Javier López-Jaramillo; Marta Rodríguez-Ruiz; Jorge Taboada; José M. Palma; Francisco J. Corpas Catalase is a major antioxidant enzyme located in plant peroxisomes that catalyzes the decomposition of H 2 O 2 . Based on our previous transcriptomic (RNA-Seq) and proteomic...

... as a novel activity of NAC. Both NAC and catalase, another known scavenger of ROS, similarly inhibited ROS levels and apoptosis associated with H 2 O 2 . However, only NAC, and not catalase or another ROS scavenger Trolox, was able to prevent effects linked to proteasome inhibition, such as protein...

...Marcel Zamocky; Paul G. Furtmüller; Marzia Bellei; Gianantonio Battistuzzi; Johannes Stadlmann; Jutta Vlasits; Christian Obinger Phytopathogenic fungi such as the rice blast fungus Magnaporthe grisea are unique in having two catalase/peroxidase (KatG) paralogues located either intracellularly...

..., but not superoxide. Furthermore, stable clones isolated from parallel studies showed significant increases in catalase and GPx (glutathione peroxidase) activity. Treatment of unstable cells with PEG-CAT (polyethylene glycol-conjugated catalase) reduced the mutation frequency and mutation rate in a dose-dependent...

... enhancement of mitochondrial O 2 •− /H 2 O 2 catabolism would delay age-associated physiological changes and extend the lifespan was tested by simultaneous overexpression of MnSOD (manganese superoxide dismutase) and catalase, ectopically targeted to the mitochondrial matrix of transgenic Drosophila...

...Gian F. GAETANI; Anna M. FERRARIS; Paola SANNA; Henry N. KIRKMAN Many catalases have the shared property of containing bound NADPH and being susceptible to inactivation by their own substrate, H 2 O 2 . The presence of additional (unbound) NADPH effectively prevents bovine liver and human...

... chemiluminescence method that allows the monitoring of H 2 O 2 generation and degradation in real time in suspensions of intact peroxisomes. Importantly, removal, as well as release of, H 2 O 2 can be assessed at nanomolar, non-toxic concentrations in the same sample. Owing to the kinetic properties of catalase...

.... The presence of reducing substrate in addition to H 2 O 2 partly or completely protected the enzyme from inactivation, depending on how many molar equivalents of reducing substrate were added. An oxygen electrode system has been used to confirm that APX does not exhibit a catalase-like oxygen-releasing...