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Keywords: catalytic activation
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Articles
Characterization of a murine gene encoding a developmentally regulated cytoplasmic dual-specificity mitogen-activated protein kinase phosphatase
Available to PurchaseRobin J. DICKINSON, David J. WILLIAMS, David N. SLACK, Jill WILLIAMSON, Ole-Morten SETERNES, Stephen M. KEYSE
Journal:
Biochemical Journal
Biochem J (2002) 364 (1): 145–155.
Published: 08 May 2002
...-specificity MKP. This enzyme selectively interacts with, and is catalytically activated by, the ‘classical’ extracellular signal-regulated kinases (ERKs) 1 and 2 and, to a lesser extent, the stress-activated MAPK p38α. These properties define the ability of this enzyme to dephosphorylate and inactivate ERK1/2...
