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Keywords: catalytic activityClose
Elina Jakobsson, Anne Jokilammi, Juha Aalto, Pauli Ollikka, Jukka V. Lehtonen, Harri Hirvonen, Jukka Finne
Biochem J (2007) 405 (3): 465–472.
Published: 13 July 2007
... for catalytically active endosialidase and polySia. The effects of the relatively conservative spontaneous mutations resemble the effects of engineered alanine-substitutions in endosialidases [ 26 ]. In PK1F the substitutions E581A, R596A or R647A reduce catalytic activity by 95% [ 26 ], and in...
Biochem J (2006) 400 (1): 99–104.
Published: 27 October 2006
... with the seed isoform 5, although the two have identical active sites. In the present study, we have investigated the contribution of non-conservative amino acid changes outside the active sites of these isoforms towards their differential catalytic activity. The saporin 6 residues Lys 134 , Leu 147...
Biochem J (2005) 391 (2): 285–289.
Published: 10 October 2005
... the biochemical properties of GPI-PLD have been extensively studied, its catalytic site has not been identified. We hypothesized that a histidine residue(s) may play a critical role in the catalytic activity of GPI-PLD, based on the observations that (i) Zn 2+ , which utilizes histidine residues for...
Zenda L. Woodman, Sylva L. U. Schwager, Pierre Redelinghuys, Adriana K. Carmona, Mario R. W. Ehlers, Edward D. Sturrock
Biochem J (2005) 389 (3): 739–744.
Published: 26 July 2005
... 2005 The Biochemical Society, London 2005 angiotensin-converting enzyme catalytic activity domain selectivity ectodomain shedding proteolytic cleavage sheddase ACE (angiotensin-converting enzyme), a zinc dipeptidyl carboxypeptidase, is responsible for the hydrolysis of...
Includes: Supplementary data
Biochem J (2003) 373 (2): 559–569.
Published: 15 July 2003
... Biochemical Society, London ©2003 2003 catalytic activity class Kappa glutathione S-transferase (GST) expression gene structure mitochondria Abbreviations used: BDNB, 1-bromo-2,4-dinitrobenzene; BLAT, basic local alignment tool; CDNB, 1-chloro-2,4-dinitrobenzene; CHP, cumene hydroperoxide...