... catalytic efficiency mechanism product specificity terpene synthase Terpenoids form the largest class of specialized or secondary metabolites and are widely used as drugs, cosmetics, and fuels [ 1 , 2 ]. Strikingly, more than 70 000 structures, accounting for 25% of known natural products...

..., which provide a potential for improving catalytic efficiency. Artemisinin, a sesquiterpene lactone from Artemisia annua L., is widely used for malaria treatment and progress has been made in engineering the production of artemisinin or its precursors. In the present paper, we report a new sesquiterpene...