... is not known to affect cell shape or motility. We report that RhoBTB1 depletion increases prostate cancer cell invasion and induces elongation in Matrigel, a phenotype similar to that induced by depletion of ROCK1 and ROCK2. We demonstrate that RhoBTB1 associates with ROCK1 and ROCK2 and its association...

..., and S100P-containing cells show enhanced activation of plasminogen compared with S100P-negative control cells. S100P shows C-terminal lysine-dependent enhancement of cell invasion. An S100P antibody, when added to the culture medium, reduced the rate of invasion of wild-type S100P-expressing cells...

... of the Biochemical Society 2017 cancer cell invasion cell proliferation chromatin reader histone modifications ZMYND8 Sustained proliferation and activated migration/invasion are two major hallmarks of cancer cells [ 1 ]. Normal tissues precisely control the cell growth and division cycle...

...Anan H. Said; Shien Hu; Ameer Abutaleb; Tonya Watkins; Kunrong Cheng; Ahmed Chahdi; Panjamurthy Kuppusamy; Neeraj Saxena; Guofeng Xie; Jean-Pierre Raufman M3 muscarinic receptor (M3R) expression is increased in colon cancer; M3R activation stimulates colon cancer cell invasion via cross-talk...

... migration and invasion. This defined a signature of signalling events that may be exploited for selective targeting of MIM-deficient metastatic tumours. breast cancer cell invasion cell migration metastasis metastasis suppressor 1 (MTSS1) Missing in Metastasis (MIM) protein tyrosine phosphatase...

... as * P <0.05 or ** P <0.01. A P value of <0.05 was considered statistically significant. © The Authors Journal compilation © 2013 Biochemical Society 2013 cell migration cell invasion F-box and WD-repeat domain-containing 2 (FBW2) glial cell missing 1 (GCM1) placenta...

... small surface antigen I (TSSA I) have been deposited in the DDBJ, EMBL, GenBank® and GSDB Nucleotide Sequence Databases under accession number JQ354939. calcium cell invasion mucin Trypanosoma cruzi trypomastigote small surface antigen (TSSA) HeLa cells grown in DMEM were serum...

... cytoskeletal re-organization through the activity of Cdc42 (cell division cycle 42) and Rac1 small GTPases, events closely associated with cell migration. cell invasion cytoskeleton dimer extracellular matrix (ECM) fluorescence resonance energy transfer (FRET) membrane-type 1 matrix...

... cancer cell invasion cell polarity PDZ domain tumour virus The PDZ domain-containing family of proteins were first recognized in the early 1990s and were classified as such, by having stretches of amino acids in common with the first such members to be identified, PSD95 (postsynaptic density...

... to this work. 2 To whom correspondence should be addressed (email [email protected] ). 18 4 2011 2 6 2011 10 6 2011 10 6 2011 Anopheles cell invasion glycobiology glycos-aminoglycan (GAG) heparan sulfate (HS) malaria Malaria transmission entails development...

... of the weakly invasive cells dependent on its demethylase activity. PLU1 was shown to repress the expression of the KAT5 gene through its H3K4 demethylation on the promoter. The regulation of KAT5 by PLU1 was suggested to be responsible for PLU1-induced cell invasion. First, knockdown of KAT5 similarly...