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1-11 of 11
Keywords: cell motility
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Articles
Journal:
Biochemical Journal
Biochem J (2017) 474 (16): 2841–2859.
Published: 10 August 2017
... of the microtubule-associated protein family and that it regulates the assembly and dynamics of microtubules. cell motility centrosome microtubule-associated proteins microtubule dynamics HeLa cell lysate was prepared in GST lysis buffer [20 mM Tris (pH 8.0), 200 mM NaCl, 0.1% Triton X-100 and 2 mM PMSF...
Includes: Supplementary data
Articles
Marina A. Guvakova, William S. Y. Lee, Dana K. Furstenau, Indira Prabakaran, David C. Li, Rupert Hung, Natasha Kushnir
Journal:
Biochemical Journal
Biochem J (2014) 463 (2): 257–270.
Published: 22 September 2014
... by putative Rap1 GTPase-activating protein (GAP). Additionally, IGF-IR signalling recruits active Rap1 at sites of cell motile protrusions. C3G depletion prevents IGF-I-induced fascin accumulation at actin microspikes and blocks protrusions. In the absence of IGF-IR activity, the wild-type (WT) Rap1...
Includes: Multimedia, Supplementary data
Articles
Sabine Windhorst, Christine Blechner, Hong-Ying Lin, Christian Elling, Marcus Nalaskowski, Tanja Kirchberger, Andreas H. Guse, Georg W. Mayr
Journal:
Biochemical Journal
Biochem J (2008) 414 (3): 407–417.
Published: 27 August 2008
...). These results clearly reveal that only overexpression of IP3K isoform A induces the formation of extended branching protrusions in H1299 cells. Since it is known that the ability to form filopodia and lamellipodia facilitates cell motility [ 29 ], we examined the impact of increased IP3K-A expression...
Articles
Journal:
Biochemical Journal
Biochem J (2007) 408 (1): 7–18.
Published: 29 October 2007
... by autoradiography. Subsequently, the Mef2 protein bands were excised from the gel and counted in a β-scintillation counter. Control assays, prepared with buffer instead of cell extract, were run in parallel, counted and subtracted from the c.p.m. of the assays. cell motility cell survival extracellular...
Articles
Journal:
Biochemical Journal
Biochem J (2005) 385 (3): 737–744.
Published: 24 January 2005
...Shin-ya NAGASAWA; Noriko TAKUWA; Naotoshi SUGIMOTO; Hiroshi MABUCHI; Yoh TAKUWA cAMP has been found to play a role in mediating the negative regulation of cell motility, although its underlying molecular mechanism remains poorly understood. By using CHO (Chinese-hamster ovary) cells that express...
Articles
Journal:
Biochemical Journal
Biochem J (2004) 382 (2): 717–723.
Published: 24 August 2004
... cell motility in MDCK cells was completely inhibited by dimethylsphingosine, a specific inhibitor of SPHK1. These results strongly suggest that at least some of δ-catenin/NPRAP functions, including increased cell motility, are mediated by an SPHK–SPP signalling pathway. The FLAG–δ-catenin/NPRAP, FLAG...
Articles
Journal:
Biochemical Journal
Biochem J (2004) 382 (1): 13–25.
Published: 10 August 2004
... cell motility endocytosis Src suppressor of cAMP receptor (SCAR)/WASP family verprolin homologous (WAVE) Wiskott–Aldrich syndrome protein (WASP) Dynamic actin networks perform a critical role in a variety of cellular processes requiring plasma membrane remodelling or intracellular movement...
Articles
Journal:
Biochemical Journal
Biochem J (2003) 374 (3): 697–705.
Published: 15 September 2003
..., London ©2003 The Biochemical Society, London © 2003 calmodulin cell motility cytoskeleton Dictyostelium discoideum myosin light chain Abbreviations used: CTER, calmodulin, troponin C, myosin II ELC and RLC; ECL®, enhanced chemiluminescence; ELC, essential light chain; ESI...
Articles
Journal:
Biochemical Journal
Biochem J (2003) 370 (2): 551–556.
Published: 01 March 2003
...-mail [email protected] ). 7 10 2002 11 11 2002 12 11 2002 12 11 2002 The Biochemical Society, London ©2003 2003 cell motility diphosphorylation monophosphorylation wound healing Abbreviations used: GFP, green fluorescent protein; MEM, minimal essential...
Articles
Journal:
Biochemical Journal
Biochem J (2002) 365 (1): 147–155.
Published: 01 July 2002
...-mail [email protected] ). 2 Present address: Medical & Biological Laboratories Co., Ltd., 1063-103, Ohara, Terasawaoka, Ina-city, 396-0002, Japan. 7 2 2002 6 3 2002 3 4 2002 The Biochemical Society, London ©2002 2002 actin-binding protein cell motility cell...
Articles
Journal:
Biochemical Journal
Biochem J (2000) 346 (3): 623–630.
Published: 07 March 2000
...Paul D. WAGNER; Ngoc-Diep VU nm23 genes have been implicated in the suppression of tumour metastasis and cell motility; however, the biochemical mechanisms for these suppressions are not known. We have previously described the transfer of phosphate from the catalytic histidine residues of nm23...