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Keywords: cell survival
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Biochem J (2022) 479 (22): 2345–2349.
Published: 23 November 2022
... University in an all-inclusive Read & Publish agreement with Portland Press and the Biochemical Society. cell survival DNA damage DNA replication and recombination inhibitor resistance Pharmacological inhibition of kinase activity has revolutionized the way we dissect the function...
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Biochem J (2012) 448 (1): 165–169.
Published: 18 October 2012
...-cells increase following BCR engagement and are characterized by a metabolic switch to aerobic glycolysis; however, the signalling pathways involved in this metabolic reprogramming are poorly defined. The PKC (protein kinase C) family plays an integral role in B-cell survival and antigenic responses...
Includes: Supplementary data
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Biochem J (2008) 415 (2): 265–273.
Published: 25 September 2008
..., whose mechanisms are not completely defined. In the present study we show that the uPA (urokinase-type plasminogen activator)/uPAR (uPA receptor) system can initiate both cell survival and pro-apoptotic signals in human MCs in response to different apoptotic stimuli. uPA abrogated MC apoptosis induced...
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Biochem J (2007) 408 (1): 7–18.
Published: 29 October 2007
...) and left for 5 h, with addition of 300 nM PMA after 1 h [ 16 ]. The extraction buffer contained 1 μM okadaic acid, to preserve serine and threonine phosphorylation, and no sodium orthovanadate, to favour FAK dephosphorylation on tyrosine (see Figure 1 B and [ 16 ]). cell motility cell survival...
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Biochem J (2005) 388 (3): 827–834.
Published: 07 June 2005
... To whom correspondence should be addressed (email scott.summers@hsc.utah.edu ). 12 10 2004 4 2 2005 7 2 2005 7 2 2005 The Biochemical Society, London 2005 cell-cycle arrest cell growth cell survival myristoylation sphingolipid sphingosine A total of 5000...
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Biochem J (2003) 369 (1): 1–15.
Published: 01 January 2003
... in part in this ability to protect cellular proteins from caspase action. Furthermore, this anti-apoptotic function of CK2 may contribute to its ability to participate in transformation and tumorigenesis. Key words: apoptosis, cell cycle, cell survival, dual-specificity kinase, phosphorylation. cellular...
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Biochem J (2002) 365 (1): 147–155.
Published: 01 July 2002
...: actin-binding protein, cell motility, cell survival, cytoskeleton, destrin. which harbour characteristic functional defects, and compared them with a previously reported mutant, which possesses enor- mously reduced filament-severing activity (A120-cofilin). Based on extensive biochemical analyses, we...
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Biochem J (2001) 359 (1): 119–127.
Published: 24 September 2001
...Alison O'TOOLE; S. Kelly MOULE; Peter J. LOCKYER; Andrew P. HALESTRAP Tumour necrosis factor-α (TNF-α) may activate both cell survival and cell death pathways. In the murine fibrosarcoma cell line WEHI-164, physiological concentrations (1ng/ml) of TNF-α induced wortmannin-sensitive cell ruffling...
Includes: Supplementary data
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