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Keywords: cell-penetrating peptides
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Articles

Stereochemistry as a determining factor for the effect of a cell-penetrating peptide on cellular viability and epithelial integrity

Ditlev Birch, Malene V. Christensen, Dan Staerk, Henrik Franzyk, Hanne Mørck Nielsen
Journal: Biochemical Journal
Biochem J (2018) 475 (10): 1773–1788.
https://doi.org/10.1042/BCJ20180155
Published: 24 May 2018
...Ditlev Birch; Malene V. Christensen; Dan Staerk; Henrik Franzyk; Hanne Mørck Nielsen Cell-penetrating peptides (CPPs) comprise efficient peptide-based delivery vectors. Owing to the inherent poor enzymatic stability of peptides, CPPs displaying partial or full replacement of l -amino acids...
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Includes: Supplementary data
Articles

Metabolic cleavage of cell-penetrating peptides in contact with epithelial models: human calcitonin (hCT)-derived peptides, Tat(47–57) and penetratin(43–58)

Rachel TRÉHIN, Hanne M. NIELSEN, Heinz-Georg JAHNKE, Ulrike KRAUSS, Annette G. BECK-SICKINGER, Hans P. MERKLE
Journal: Biochemical Journal
Biochem J (2004) 382 (3): 945–956.
https://doi.org/10.1042/BJ20040238
Published: 07 September 2004
...Rachel TRÉHIN; Hanne M. NIELSEN; Heinz-Georg JAHNKE; Ulrike KRAUSS; Annette G. BECK-SICKINGER; Hans P. MERKLE We assessed the metabolic degradation kinetics and cleavage patterns of some selected CPP (cell-penetrating peptides) after incubation with confluent epithelial models. Synthesis of N...
View articletitled, Metabolic cleavage of cell-penetrating peptides in contact with epithelial models: human calcitonin (hCT)-derived peptides, Tat(47–57) and penetratin(43–58)
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