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Keywords: chemoresistance
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Articles
EZH2 promotes chemoresistance in colorectal cancer by inhibiting autophagy through NRP1 suppression
Open Access
Journal:
Biochemical Journal
Biochem J (2025) 482 (10): 569–581.
Published: 14 May 2025
...Hong Deng; Qin Xu; Qiang Zhang; Chunfeng Liu; Lei Ren Colorectal cancer (CRC) is characterized by aggressive tumor growth and chemoresistance, with enhancer of zeste homolog 2 (EZH2) serving a pivotal role in these processes. However, the mechanisms by which it drives tumor proliferation...
Includes: Supplementary data
Articles
Structural basis for the bypass of the major oxaliplatin–DNA adducts by human DNA polymerase η
Available to PurchaseIn Collection
Editors' pick of research highlights published in the Biochemical Journal in 2018 & 2019
Journal:
Biochemical Journal
Biochem J (2019) 476 (4): 747–758.
Published: 28 February 2019
..., and the refined models were summarized in Table 1 . Correspondence: Seongmin Lee ( [email protected] ) 2 11 2018 23 1 2019 1 2 2019 1 2 2019 © 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2019 chemoresistance...
Includes: Supplementary data
Articles
Targeting epithelial–mesenchymal plasticity in cancer: clinical and preclinical advances in therapy and monitoring
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2017) 474 (19): 3269–3306.
Published: 20 September 2017
... are required for invasion, dissemination, survival and colonisation at distant sites. EMP also influences resistance to anoikis, enhances survival, creates genomic instability and induces resistance to chemotherapies (reviewed in refs [ 33 , 34 ]). chemoresistance CSC CTC EMT MET Worldwide...
Articles
Biochemical role of the collagen-rich tumour microenvironment in pancreatic cancer progression
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2012) 441 (2): 541–552.
Published: 21 December 2011
... examine the way in which signalling events through these pathways mediates invasion, regulates microRNAs and contributes to chemoresistance. 1 Correspondence may be addressed to either of these authors (email [email protected] or [email protected] ). 11 7 2011...
Includes: Multimedia, Supplementary data