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Keywords: cholesterol transport
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Biochem J (2007) 408 (1): e1.
Published: 29 October 2007
... in intracellular cholesterol transport and could potentially influence NPC1L1-mediated cholesterol uptake are NPC1 and NPC2 (Niemann–Pick type C disease proteins 1 and 2). In this issue of the Biochemical Journal , Dixit and colleagues show that the absence or presence of NPC1 and NPC2 has no effect on intestinal...
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Biochem J (2007) 408 (1): 1–5.
Published: 29 October 2007
... in enterocytes via NPC1L1 (3), cholesterol is transported to the endoplasmic reticulum (ER) by pathways that might bypass (4) or involve (5) the endosomal (LE)/lysosomal (LYS) system. In the latter case, NPC1, a lysosomal cholesterol transporter, and NPC2 would be required for egress cholesterol from...