1-11 of 11
Keywords: colorectal cancer
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Biochem J (2020) 477 (12): 2281–2293.
Published: 24 June 2020
... is decreased in colorectal cancer (CRC) tumor tissues, compared with normal pairs. Furthermore, RT-qPCR and western blot analysis showed that the OCT4 gene has been down-regulated following the miR-3658 overexpression. Consistently, dual-luciferase assay supported the direct interaction of miR-3658 with the 3...
Articles
Biochem J (2019) 476 (5): 779–781.
Published: 06 March 2019
...Phillip T. Newton Colorectal cancer is one of the most common forms of cancer in the world, with more than half a million new cases annually. Amongst the most promising new therapies, niclosamide—an FDA-approved drug for treating tapeworm infections—is being assessed in a stage II clinical trial...
Articles
Articles
Articles
Biochem J (2018) 475 (17): 2749–2767.
Published: 05 September 2018
... of IMP1 is shown in two animal cancer models. Mice genetically engineered to carry targeted expression of IMP1 in mammary glands developed mammary adenocarcinoma [ 10 ]. The role of IMP1 in the development of colorectal cancer was suggested by the following findings: (i) in colorectal cancer cell...
Articles
Articles
Biochem J (2016) 473 (20): 3597–3610.
Published: 11 October 2016
... the possibility of miR-27a being a new regulator of p53. Using luciferase reporter assay and various mutational and functional analysis, we identified two putative binding sites of miR-27a on the 3′-UTR of p53. The overexpression of miR-27a in the human colorectal cancer cell line HCT-116 +/+ resulted...
Includes: Supplementary data
Articles
Articles
Biochem J (2009) 422 (3): 493–501.
Published: 27 August 2009
... and both proteins co-localize in SW480 colorectal cancer cells. The interaction with CBP also enhances both DNA-tethered and TCF/LEF1 (lymphoid enhancing factor 1)-dependent transcriptional activity of Pygopus. Furthermore, immunoprecipitated Pygopus protein complexes displayed CBP-dependent histone...
Includes: Supplementary data
Articles
Biochem J (2004) 379 (1): 209–216.
Published: 01 April 2004
... cancers. Two missense mutations in the C-terminal domain of Smad4, D351H (Asp 351 →His) and D537Y (Asp 537 →Tyr), have been described recently in the human colorectal cancer cell lines CACO-2 and SW948 respectively [Woodford-Richens, Rowan, Gorman, Halford, Bicknell, Wasan, Roylance, Bodmer and Tomlinson...
Articles