... monophosphate (cAMP), which governs a wide array of processes, ranging from cellular growth and survival to metabolic regulation. Studies have highlighted that cAMP is not uniformly distributed within cells but instead is compartmentalized into highly localized nanodomains. These nanodomains, mostly regulated...

[email protected] ). 30 11 2011 30 1 2012 17 2 2012 17 2 2012 © The Authors Journal compilation © 2012 Biochemical Society 2012 compartmentalization extracellular-signal-regulated kinase (ERK) Golgi apparatus progestin and adipoQ receptor 10 (PAQR10) Ras The PAQR...

.... They have lost most of their original cytoplasm, and remaining organelles are extremely modified. One result of this is that biochemical dynamics are restricted by a lack of cytoplasmic diffusion and a dramatic compartmentalization, with an increased emphasis on the physicochemical modulation of membranes...

... in NIH 3T3 cells drives translocation of PPIP5K1 from the cytosol to the plasma membrane. We have therefore demonstrated receptor-regulated compartmentalization of inositol pyrophosphate synthesis in mammalian cells. 1 These two authors contributed equally to this study. 2 To whom...

...Ricardo V. Ullán; Fernando Teijeira; Susana M. Guerra; Inmaculada Vaca; Juan F. Martín The mechanisms of compartmentalization of intermediates and secretion of penicillins and cephalosporins in β-lactam antibiotic-producing fungi are of great interest. In Acremonium chrysogenum...

... with an exposure time of 5 min. Acremonium chrysogenum CefM transporter cephalosporin C biosynthesis compartmentalization isopenicillin N translocation of penicillin N from microbodies Industrial production of cephalosporins is performed with the filamentous fungus Acremonium chrysogenum...

... molecules are compartmentalized. The response to NGF (nerve growth factor) is strongly dependent on the trafficking of its receptor, TrkA. However, information is still scarce about the role of the cellular localization of the TrkA co-receptor, p75 NTR (where NTR is neurotrophin receptor), following...

...Douglas L. HOGUE; Colin NASH; Victor LING; Tom C. HOBMAN Lysosome-associated protein transmembrane 4α (LAPTM4α) and homologues comprise a family of conserved proteins, which are found in mammals, insects and nematodes. LAPTM4α functions to regulate the intracellular compartmentalization...