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Keywords: complex 1
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Bruno GUIGAS, Dominique DETAILLE, Christiane CHAUVIN, Cécile BATANDIER, Frédéric De OLIVEIRA, Eric FONTAINE, Xavier LEVERVE
Journal:
Biochemical Journal
Biochem J (2004) 382 (3): 877–884.
Published: 07 September 2004
.... In the present study, the effects of metformin on respiration, complex 1 activity, mitochondrial permeability transition, cytochrome c release and cell death were investigated in cultured cells from a human carcinoma-derived cell line (KB cells). Metformin significantly decreased respiration both in intact cells...
