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Keywords: computer simulationClose
Biochem J (2011) 438 (3): 415–426.
Published: 26 August 2011
... predictions that can be tested in the laboratory. Computer simulations can nowadays provide molecular or even atomistic details that are experimentally not available or very difficult to obtain. In the present review, recent developments on modelling and experiments of amyloid aggregation are reviewed, and an...
Includes: Multimedia, Supplementary data
Biochem J (2006) 399 (2): 343–350.
Published: 27 September 2006
... diabetes and obesity. However, a complete understanding of the detailed catalytic mechanism in PTPs is still lacking. Free-energy profiles, obtained by computer simulations of catalysis by a dual-specificity PTP, are shown in the present study and are used to shed light on the catalytic mechanism. A highly...
Mariko HATAKEYAMA, Shuhei KIMURA, Takashi NAKA, Takuji KAWASAKI, Noriko YUMOTO, Mio ICHIKAWA, Jae-Hoon KIM, Kazuki SAITO, Mihoro SAEKI, Mikako SHIROUZU, Shigeyuki YOKOYAMA, Akihiko KONAGAYA
Biochem J (2003) 373 (2): 451–463.
Published: 15 July 2003
... 2003 The Biochemical Society, London ©2003 2003 computer simulation cross-talk ErbB heregulin signal transduction Abbreviations used: CHO, Chinese-hamster ovary; EGFR, epidermal growth factor receptor; ERK, extracellular signal-regulated kinase; ERKPP, phosphorylated ERK; Grb2...
Biochem J (2001) 356 (2): 433–444.
Published: 24 May 2001
...Christophe CHASSAGNOLE; David A. FELL; Badr RAÏS; Bernard KUDLA; Jean-Pierre MAZAT A computer simulation of the threonine-synthesis pathway in Escherichia coli Tir-8 has been developed based on our previous measurements of the kinetics of the pathway enzymes under near-physiological conditions. The...