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Keywords: coronavirus
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Biochem J (2022) 479 (8): 901–920.
Published: 21 April 2022
...). In this study, an in vitro colorimetric AuNP protease assay is adapted to specifically detect the protease activity of β-genera coronavirus 3CLpro enzymes. The data show specific detection of purified recombinant 3CLpro from SARS-CoV-2 and OC43 human coronaviruses, providing a clear red to blue colour change...
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Biochem J (2021) 478 (19): 3671–3684.
Published: 14 October 2021
... serve as a reservoir for bovine coronavirus (BCoV) a respiratory infection of cattle that is a betacoronavirus [ 11 , 12 ] distantly related to SARS-CoV-2 [ 7 ]. Of considerable note, two BCoV-related coronaviruses, HCoV-OC43 and HCoV-HKU1, have crossed the species barrier, with OC43 likely from cows...
Includes: Supplementary data
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Biochem J (2021) 478 (13): 2533–2535.
Published: 02 July 2021
... structures of each of the enzymes with their inhibitors to inform the chemistry required to improve inhibitor efficacy. antiviral coronavirus COVID-19 Coronaviruses encode multiple enzymes important for viral replication [ 1 ], and any of these could be attractive drug targets. We identified...
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Biochem J (2021) 478 (13): 2399–2403.
Published: 02 July 2021
...Ronald T. Hay The coronavirus pandemic has had a huge impact on public health with over 165 million people infected, 3.4 million deaths and a hugely deleterious effect on most economies. While vaccination effectively protects against the disease it is likely that viruses will evolve that can...
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Coronavirus
Biochem J (2021) 478 (1): 157–177.
Published: 13 January 2021
... ) The molecular virology of coronaviruses . J. Biol. Chem. 295 , 12910 – 12934 10.1074/jbc.REV120.013930 8 V'kovski , P. , Kratzel , A. , Steiner , S. , Stalder , H. and Thiel , V. ( 2020 ) Coronavirus biology and replication: implications for SARS-CoV-2 . Nat. Rev. Microbiol...
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Coronavirus
Biochem J (2020) 477 (8): 1479–1482.
Published: 29 April 2020
... References 1 WHO . Novel Coronavirus (2019-nCoV) situation report-77 . https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200406-sitrep-77-covid-19.pdf?sfvrsn=21d1e632_2 (Accessed on 7 April 2020) 2 Wu , F. , Zhao , S. , Yu , B. , Chen , Y.M. , Wang , W...
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Coronavirus
Biochem J (2020) 477 (5): 1009–1019.
Published: 13 March 2020
... to MERS: 10 years of research on highly pathogenic human coronaviruses . Antiviral Res. 100 , 286 – 295 10.1016/j.antiviral.2013.08.015 3 Brierley , I. , Digard , P. and Inglis , S.C. ( 1989 ) Characterization of an efficient coronavirus ribosomal frameshifting signal...
Includes: Supplementary data