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Keywords: cytochrome c oxidase
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Biochem J (2014) 459 (3): 525–538.
Published: 11 April 2014
... A domain of CcO (cytochrome c oxidase). How Sco obtains copper once secreted to the extracytoplasmic environment is unknown. In the present paper we report on a protein possessing an HX 6 MX 21 HXM motif that binds a single cuprous ion with subfemtomolar affinity. High-resolution X-ray structures...
Includes: Supplementary data
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Biochem J (2010) 427 (1): 105–112.
Published: 15 March 2010
... 344 rats. OXPHOS (oxidative phosphorylation) of intact mitochondria and cytochrome c oxidase activity in permeabilized mitochondria were determined with polarographic assays. The activities of the ETC (electron transport chain) complexes and the cytochrome content in solubilized mitochondria were...
Includes: Supplementary data
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Biochem J (2009) 417 (1): 183–193.
Published: 12 December 2008
..., accumulation of 3-NT paralleled the hypoxia gradient in vivo and 3-NT levels were increased in mitochondrial proteins. Liver mitochondria from mice fed the HFD for 16 weeks exhibited depressed state 3 respiration, uncoupled respiration, cytochrome c oxidase activity, and mitochondrial membrane potential...
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Biochem J (2005) 390 (3): 703–708.
Published: 05 September 2005
... of the yeast enzyme. 1 To whom correspondence should be addressed (email b.meunier@ucl.ac.uk ). 13 4 2005 24 5 2005 27 5 2005 27 5 2005 The Biochemical Society, London 2005 assembly blue native protein electrophoresis COX2 mutant cytochrome c oxidase haem...
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Biochem J (2005) 390 (2): 501–511.
Published: 23 August 2005
... as a function of age, using either NAD + - or FAD-linked substrates; however, there were no differences in state 4 respiration (ADP-depleted) rates. There was also a significant age-related decline in the activity of cytochrome c oxidase (complex IV), but not of the other mitochondrial oxidoreductases examined...
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Biochem J (2004) 382 (3): 923–932.
Published: 07 September 2004
... and immunoprecipitation analyses indicated that the protein is subunit IV of the cytochrome c oxidase complex (COIV). In vitro phosphorylation of COIV was attenuated by PKC pseudosubstrate peptides. Introduction of an PKCε-selective translocation inhibitor [Johnson, Gray, Chen and Mochly-Rosen (1996) J. Biol. Chem. 271...
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Biochem J (2003) 376 (2): 537–544.
Published: 01 December 2003
...) stabilize HIF-1α at all O 2 concentrations tested. This effect does not involve the respiratory chain, since it is preserved in cells lacking functional mitochondria (ρ 0 -cells) and is not reproduced by other inhibitors of the cytochrome c oxidase. By contrast, lower concentrations of NO (<400 nM) cause...
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Biochem J (2001) 354 (2): 407–412.
Published: 22 February 2001
... assembly. The change Gly-317 → Ser had no effect on respiratory function. However, mutations Met-273 → Thr and Ile-280 → Thr were mildly deleterious, decreased cytochrome oxidase activity and slightly perturbed the properties of the binuclear centre. cytochrome c oxidase disease-associated mutations...
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Biochem J (2000) 352 (1): 109–115.
Published: 07 November 2000
...´-UTRs of nuclear-encoded mRNAs involved in the biogenesis of mitochondria have an intrinsic TEA. TEA is found in the 3´-UTR of the mRNAs encoding the α- and β-subunits of the rat H + -ATP synthase complex, as well as in subunit IV of cytochrome c oxidase. No TEA is present in the 3´-UTR of the somatic...