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1-4 of 4
Keywords: deacetylation
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Articles
SIRT3 interactions with FOXO3 acetylation, phosphorylation and ubiquitinylation mediate endothelial cell responses to hypoxia
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2014) 464 (1): 157–168.
Published: 23 October 2014
... FOXO3 is deacetylated by SIRT3. The SIRT3-mediated deacetylation of FOXO3 further reduces FOXO3 phosphorylation, ubiquitination and degradation, thereby stabilizing FOXO3 proteins. As a result, the level of FOXO3 protein is increased during hypoxia. Moreover, a set of FOXO3-dependent mitochondrial...
Includes: Supplementary data
Articles
Where in the cell is SIRT3? – functional localization of an NAD + -dependent protein deacetylase
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2008) 411 (2): e11–e13.
Published: 27 March 2008
.... Recently, a report comparing SIRT3 −/− and SIRT +/+ mice have provided compelling evidence that endogenous SIRT3 is mitochondrial and appears to be responsible for the majority of protein deacetylation in this organelle. In this issue of the Biochemical Journal , Cooper et al. present additional results...
Articles
Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors
Available to PurchaseNagma Khan, Michael Jeffers, Sampath Kumar, Craig Hackett, Ferenc Boldog, Nicholai Khramtsov, Xiaozhong Qian, Evan Mills, Stanny C. Berghs, Nessa Carey, Paul W. Finn, Laura S. Collins, Anthony Tumber, James W. Ritchie, Peter Buhl Jensen, Henri S. Lichenstein, Maxwell Sehested
Journal:
Biochemical Journal
Biochem J (2008) 409 (2): 581–589.
Published: 21 December 2007
.... deacetylation histone deacetylase (HDAC) histone deacetylase isoforms (HDAC isoforms) small-molecule inhibitors tubulin HDACs (histone deacetylases) are a family of enzymes involved in the regulation of a number of cellular processes [ 1 ], including cell proliferation, apoptosis and assembly...
Includes: Supplementary data
Articles
Stimulation of glycosylphosphatidylinositol biosynthesis in mammaliancell-free systems by GTP hydrolysis: evidence for the involvement of membrane fusion
Available to Purchase
Journal:
Biochemical Journal
Biochem J (1999) 341 (3): 577–584.
Published: 26 July 1999
...Victoria L. STEVENS; Hui ZHANG; Eva Szucs KRISTYANNE The second step in glycosylphosphatidylinositol (GPI) biosynthesis, the deacetylation of GlcNAc-phosphatidylinositol (GlcNAc-PI), has been shown to be stimulated by GTP hydrolysis [Stevens (1993) J. Biol. Chem. 268 , 9718-9724]. We have now...