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1-6 of 6
Keywords: diabetic nephropathy
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Articles
Epigenetic changes and alteration of Fbn1 and Col3A1 gene expression under hyperglycaemic and hyperinsulinaemic conditions
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2010) 432 (2): 333–341.
Published: 12 November 2010
... by activating different signalling pathways that specifically drive transcription of downstream pathogenic factors and genes. DN (diabetic nephropathy) affects 30% of diabetic patients and has become the leading cause of end-stage kidney disease worldwide [ 1 , 2 ]. Patients with different stages of DN...
Includes: Supplementary data
Articles
High ambient glucose induces angiotensin-independent AT-1 receptor activation, leading to increases in proliferation and extracellular matrix accumulation in MES-13 mesangial cells
Available to PurchaseNaohiro Yano, Daisuke Suzuki, Masayuki Endoh, Tram N. Cao, John R. Dahdah, Andy Tseng, Joan P. Stabila, Bethany G. McGonnigal, James F. Padbury, Yi-Tang Tseng
Journal:
Biochemical Journal
Biochem J (2009) 423 (1): 129–143.
Published: 14 September 2009
...Naohiro Yano; Daisuke Suzuki; Masayuki Endoh; Tram N. Cao; John R. Dahdah; Andy Tseng; Joan P. Stabila; Bethany G. McGonnigal; James F. Padbury; Yi-Tang Tseng Diabetic nephropathy is associated with mesangial ECM (extracellular matrix) accumulation. We have shown that AT-1R [Ang II (angiotensin II...
Articles
Glucosamine induces cell-cycle arrest and hypertrophy of mesangial cells: implication of gangliosides
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2005) 388 (2): 537–544.
Published: 24 May 2005
...Elodie MASSON; Nicolas WIERNSPERGER; Michel LAGARDE; Samer El BAWAB Alterations in proliferation and hypertrophy of renal mesangial cells are typical features of diabetic nephropathy. The HP (hexosamine pathway) has been proposed as a biochemical hypothesis to explain microvascular alterations due...
Articles
Thrombospondin-1 mediates distal tubule hypertrophy induced by glycated albumin
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2004) 379 (1): 89–97.
Published: 01 April 2004
...Yu-Lin YANG; Lea-Yea CHUANG; Jinn-Yuh GUH; Shu-Fen LIU; Min-Yuan HUNG; Tung-Nan LIAO; Yu-Lun HUANG Diabetic nephropathy is characterized by early hypertrophy in both glomerular and tubuloepithelial elements. However, no studies to date have established a direct causal link between hyperglycaemia...
Articles
Regulation of type II transforming-growth-factor-β receptors by protein kinase C ι
Available to PurchaseLea-Yea CHUANG, Jinn-Yuh GUH, Shu-Fen LIU, Min-Yuan HUNG, Tung-Nan LIAO, Tai-An CHIANG, Jau-Shyang HUANG, Yu-Lun HUANG, Chi-Fong LIN, Yu-Lin YANG
Journal:
Biochemical Journal
Biochem J (2003) 375 (2): 385–393.
Published: 15 October 2003
...Lea-Yea CHUANG; Jinn-Yuh GUH; Shu-Fen LIU; Min-Yuan HUNG; Tung-Nan LIAO; Tai-An CHIANG; Jau-Shyang HUANG; Yu-Lun HUANG; Chi-Fong LIN; Yu-Lin YANG TGF-β (transforming growth factor-β) is implicated in the pathogenesis of diabetic nephropathy. We previously demonstrated that up-regulation of type II...
Articles
Role of the Janus kinase (JAK)/signal transducters and activators of transcription (STAT) cascade in advanced glycation end-product-induced cellular mitogenesis in NRK-49F cells
Available to PurchaseJau-Shyang HUANG, Jinn-Yuh GUH, Wen-Chun HUNG, Mei-Li YANG, Yung-Hsiung LAI, Hung-Chun CHEN, Lea-Yea CHUANG
Journal:
Biochemical Journal
Biochem J (1999) 342 (1): 231–238.
Published: 10 August 1999
...Jau-Shyang HUANG; Jinn-Yuh GUH; Wen-Chun HUNG; Mei-Li YANG; Yung-Hsiung LAI; Hung-Chun CHEN; Lea-Yea CHUANG Advanced glycation end product (AGE) is important in the pathogenesis of diabetic nephropathy, which is characterized by cellular hypertrophy/hyperplasia leading to renal fibrosis. However...
