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Keywords: diacylglycerol acyltransferase
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Articles

Hepatic triacylglycerol synthesis and secretion: DGAT2 as the link between glycaemia and triglyceridaemia

Victor A. Zammit
Journal: Biochemical Journal
Biochem J (2013) 451 (1): 1–12.
https://doi.org/10.1042/BJ20121689
Published: 14 March 2013
...Victor A. Zammit The liver regulates both glycaemia and triglyceridaemia. Hyperglycaemia and hypertriglyceridaemia are both characteristic of (pre)diabetes. Recent observations on the specialised role of DGAT2 (diacylglycerol acyltransferase 2) in catalysing the de novo synthesis...
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Articles

Regulation of the enzymes of hepatic microsomal triacylglycerol lipolysis and re-esterification by the glucocorticoid dexamethasone

Vernon W. DOLINSKY, Donna N. DOUGLAS, Richard LEHNER, Dennis E. VANCE
Journal: Biochemical Journal
Biochem J (2004) 378 (3): 967–974.
https://doi.org/10.1042/bj20031320
Published: 15 March 2004
... decrease in TGH mRNA stability. The expression and activities of diacylglycerol acyltransferases 1 and 2 were stimulated by dexamethasone. The combination of reduced intracellular TAG lipolysis and increased TAG biosynthesis contributed to the accumulation of TAG within the livers of dexamethasone-injected...
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