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Keywords: dimethylfumarate
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Gerardo G. Piroli, Allison M. Manuel, Michael D. Walla, Matthew J. Jepson, Jonathan W. C. Brock, Mathur P. Rajesh, Ross M. Tanis, William E. Cotham, Norma Frizzell
Journal:
Biochemical Journal
Biochem J (2014) 462 (2): 231–245.
Published: 07 August 2014
... [S-(2-succino)cysteine]. We demonstrate that both α- and β-tubulin are increasingly modified by succination in 3T3-L1 adipocytes and in the adipose tissue of db / db mice. Incubation of purified tubulin from porcine brain with fumarate (50 mM) or the pharmacological compound DMF (dimethylfumarate...
