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Keywords: double-stranded RNA
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Articles
Oligomerization of bovine ribonuclease A: structural and functional features of its multimers
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2004) 380 (2): 311–327.
Published: 01 June 2004
...) domain-swapping mechanism, are described and discussed. Attention is also focused on some functional properties of the RNase A oligomers. Their enzymic activities, particularly their ability to degrade double-stranded RNAs and polyadenylate, are summarized and discussed. The same is true...
Articles
The C-terminal, third conserved motif of the protein activator PACT plays an essential role in the activation of double-stranded-RNA-dependent protein kinase (PKR)
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2002) 366 (1): 175–186.
Published: 15 August 2002
...Xu HUANG; Brian HUTCHINS; Rekha C. PATEL One of the key mediators of the antiviral and antiproliferative actions of interferon is double-stranded-RNA-dependent protein kinase (PKR). PKR activity is also involved in the regulation of cell proliferation, apoptosis and signal transduction. We have...
Articles
α-, β- or γ-chain-specific RNA interference of laminin assembly in Drosophila Kc167 cells
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Journal:
Biochemical Journal
Biochem J (2001) 360 (1): 167–172.
Published: 08 November 2001
...Akira GOTO; Makoto AOKI; Shigeyuki ICHIHARA; Yasuo KITAGAWA Drosophila laminin αβγ trimer assembly in Kc167 cells was perturbed by chain-specific RNA interference (RNAi). The intracellular pool of α and γ chains remained unchanged under β-chain RNAi by lipofection of double-stranded RNA encoding...