...). Conversely, RPV- and EFV-resistant strains were fully sensitive to DOR. Nowadays, CADD is widely applied to the rationalization and speeding up of the drug development process, starting from the promising hits obtained by high-throughput enzymatic assays or virtual screening approaches of libraries...

... chemical entities’ (e.g. MAL3-101, equisetin and CJ-21,058) for anti-trypanosome drug development. 1 These authors contributed equally to this work. 2 Present address: Department of Medical Education, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, 5001 El...