... Biochemical Society 2014 Our findings identified a key role of Drp1 in the induction of mitochondria-related necrosis under conditions of oxidative stress in vitro and in vivo , suggesting that Drp1 might be a useful target to combat necrosis in human disease. dynamin-related protein 1 (Drp1...

... disruption in skeletal muscle. ceramide dynamin-related protein 1 (Drp1) mitochondrion mitochondrial fission metabolic disruption The current worldwide trends of increasing prevalence of obesity and Type 2 diabetes suggest the complexity of the problem and the need for intensive research...