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Keywords: ecto-kinase
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Articles
Design, validation and efficacy of bisubstrate inhibitors specifically affecting ecto-CK2 kinase activity
Available to PurchaseGiorgio Cozza, Sofia Zanin, Stefania Sarno, Elena Costa, Cristina Girardi, Giovanni Ribaudo, Mauro Salvi, Giuseppe Zagotto, Maria Ruzzene, Lorenzo A. Pinna
Journal:
Biochemical Journal
Biochem J (2015) 471 (3): 415–430.
Published: 16 October 2015
...-substrate directed derivative has been designed. It is active on cellular ecto-CK2 and its multifunctional mode of binding has been determined by kinetic and mutational analyses. bisubstrate inhibitor cell migration CK2 ecto-kinase protein kinase inhibitor protein phosphorylation signal...
