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Keywords: effector functions
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Articles
Getting oriented with antibodies
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2017) 474 (4): 517–519.
Published: 03 February 2017
... full length antibodies bound simultaneously to fHbp. This revealed that the bound antibodies orient their Fc domains 115–130 Å apart, a distance that is compatible with multivalent C1q binding. The need for a precise orientation of Fc domains in order to efficiently activate effector functions...
