... conformational changes enzyme–substrate interactions phosphorylation small-molecule inhibitor ULK kinase Membrane abscission is the ultimate step in several physiologically important processes such as exosome budding and cytokinesis [ 1 ]. Any connection between two membrane substructures is cut...

... Society 2021 crystallography enzyme–substrate interactions glycoside hydrolase molecular mechanisms NAD-dependent The glycoside hydrolases (GHs) constitute a large group of enzymes of 167 GH families classified currently in the carbohydrate active enzyme database (CAZy) [ 1 , 2...

... Society 2019 carnitine biosynthesis enzyme–substrate interactions hydroxylation mutagenesis Carnitine ( l -3-hydroxy-4- N , N , N -trimethylaminobutyrate) is an important metabolite that facilitates the transport of long fatty acids from the cytosol into mitochondria in humans, other...

... theory enzyme kinetics enzyme–substrate interactions molecular dynamics thermodynamics translation factors © 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2019 30 11 2018 28 1 2019 1 2 2019 1 2 2019 * These authors...

...–substrate interactions polyamines small-angle scattering The ubiquitous polyamine biosynthesis route in eukaryota, which yields the simple diamine putrescine [PUT, NH 2 (CH 2 ) 4 NH 2 ], relies on the decarboxylation of ornithine by ornithine decarboxylase (EC 4.1.1.17). Ornithine is produced from...