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Keywords: enzyme inhibitor
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Biochem J (2019) 476 (22): 3505–3520.
Published: 27 November 2019
... similar to AnCE. In addition, important elements that differ in these structures provide information that could potentially be utilised in the design of chemical leads for selective mosquitocide development. enzyme inhibitor insecticide design metalloprotease mosquito control protein...
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Biochem J (2018) 475 (20): 3221–3238.
Published: 23 October 2018
..., leading to genome hypermethylation [ 11 , 12 ]. cancer metabolism enzyme inhibitor enzyme kinetics enzyme mutation IDH1 molecular dynamics © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2018 6 6 2018 14 9 2018 18 9 2018...
Includes: Supplementary data
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Biochem J (2016) 473 (14): 2023–2032.
Published: 12 July 2016
... capture drug enzyme inhibitor metalloenzyme X-ray crystallography The carbonic anhydrases (CAs, EC 4.2.1.1) belong to a superfamily of metalloenzymes which use as substrates some unusually chemically simple molecules/ions, as they catalyse the interconversion between CO 2 and bicarbonate [ 1...
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Biochem J (2003) 373 (1): 231–239.
Published: 01 July 2003
...-methylcoumaryl-7-amide; RP-HPLC, reversed-phase HPLC; MALDI-TOF, matrix-assisted laser-desorption ionization–time-of-flight; hfurin, human furin; pro-PTH, proparathyroid hormone; QFS-8, (Abz-Gly-Ser-Arg-Lys-Lys-Arg↓Ser-Val-Ser-Glu-3-nitrotyrosine-Ser, where Abz is 2-aminobenzoic acid). enzyme inhibitor...
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Biochem J (2002) 367 (2): 329–334.
Published: 15 October 2002
...-binding site) appears to have a pocket that could bind oleic acid, with the pocket being 8.50Å long and 12.80Å wide. The Biochemical Society, London ©2002 2002 computer modelling enzyme inhibitor oleic acid RNA-dependent DNA polymerase Abbreviations used: 3D, three-dimensional; RT...
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Biochem J (2000) 350 (3): 757–763.
Published: 08 September 2000
... topoisomerases I and II enzyme inhibitor Biochem. J. (2000) 350, 757 763 (Printed in Great Britain) 757 Novel triterpenoids inhibit both DNA polymerase and DNA topoisomerase Yoshiyuki MIZUSHINA*, Akira IIDA‹, Keisuke OHTA*, Fumio SUGAWARA* and Kengo SAKAGUCHI*1 *Department of Applied Biological Science...
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Biochem J (2000) 350 (1): 81–88.
Published: 09 August 2000
... against OA binds to TM2 albeit with much lower affinity than to OA, whereas it exhibits no measurable affinities to TM and TM1. Key words: enantiomer, enzyme inhibitor, okadaic acid, structure affinity relationship. the catalytic centre of the enzyme (see Discussion). We therefore expected that chemical...