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Keywords: enzyme mechanism
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Articles
Biochem J (2018) 475 (23): 3861–3873.
Published: 10 December 2018
... Portland Press Limited on behalf of the Biochemical Society 2018 acyl-ACP thioesterase enzyme catalysis enzyme mechanism fatty acid synthase site-directed mutagenesis Correspondence: Basil J. Nikolau ( dimmas@iastate.edu ) or Marna D. Yandeau-Nelson ( myn@iastate.edu ) 17 6...
Includes: Supplementary data
Articles
Biochem J (2018) 475 (22): 3651–3667.
Published: 30 November 2018
... Society 2018 crystal structure enzyme mechanism thiamine diphosphate vitamin K MenD, or 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) synthase, is involved in the biosynthesis of menaquinone or vitamin K2 [ 1 – 4 ]. It is a thiamine diphosphate (ThDP)-dependent...
Articles
Biochem J (2018) 475 (10): 1821–1837.
Published: 31 May 2018
... concentration of PEP (0.5 mM) and ADP (0.4 mM). For these uncompetitive inhibitors the K i values were calculated to be equal to IC 50 /2. allostatic regulation amino-acid regulation enzyme mechanism pyruvate kinase In the 1920s, Otto Warburg observed that cancer cells produce ATP mainly...
Includes: Multimedia, Supplementary data
Articles
Biochem J (2016) 473 (5): 651–660.
Published: 24 February 2016
...-orotate dehydrogenase enzyme mechanism flavoprotein Leishmania major nucleoside/nucleotide biosynthesis Dihydro-orotate dehydrogenases (DHODHs) catalyse the fourth and only redox reaction in the de novo pyrimidine biosynthetic pathway, the stereoselective oxidation of ( S )-dihydro-orotate...
Includes: Supplementary data
Articles
Biochem J (2015) 472 (3): 297–307.
Published: 27 November 2015
... basis for substrate binding and allowed us to present a reaction mechanism for the enzyme. carbohydrate crystal structure enzyme mechanism glucose-fructose oxidoreductase/inositol dehydro-genase/rhizopine catabolism protein (Gfo/Idh/MocA) family oxidoreductase reduced nicotinamide-adenine...
Articles
Biochem J (2011) 440 (1): 13–21.
Published: 27 October 2011
... one pocket active at any given time. This one-third-of-the-sites reactivity enzyme mechanism was verified further by hybridization experiments and MD simulations. The results of the present study revealed for the first time a novel one-third-of-the-sites reactivity enzyme mechanism for mPGES-1, and...
Includes: Supplementary data
Articles
Biochem J (2010) 425 (3): 513–522.
Published: 15 January 2010
... 2009 3 11 2009 3 11 2009 © The Authors Journal compilation © 2010 Biochemical Society 2010 Chagas disease enzyme mechanism NMR spectroscopy peroxidase X-ray crystallography Across the tropics over 20 million people are infected by the protozoan parasites Trypanosoma...
Includes: Supplementary data
Articles
Biochem J (2010) 425 (2): 327–339.
Published: 23 December 2009
... of complex I, and describes and discusses contemporary mechanistic hypotheses, proposals and models. 1 email jh@mrc-mbu.cam.ac.uk 3 9 2009 30 9 2009 © The Authors Journal compilation © 2010 Biochemical Society 2010 electron transport chain enzyme mechanism...
Articles
Biochem J (2009) 420 (1): 27–35.
Published: 28 April 2009
... required to eliminate competing host mRNAs and to allow stage-specific synthesis of viral proteins [ 8 ]. decapping enzyme enzyme mechanism mRNA metabolism Nudix motif structural modelling vaccinia virus This work was supported by a grant from the Canadian Institutes for Health Research...
Includes: Supplementary data
Articles
Biochem J (2009) 417 (1): 103–114.
Published: 12 December 2008
...@manchester.ac.uk ). 28 2 2008 22 8 2008 3 9 2008 3 9 2008 © The Authors Journal compilation © 2009 Biochemical Society 2009 adrenodoxin reductase coenzyme binding electron transfer enzyme mechanism flavoprotein reductase A Mycobacterium tuberculosis Mtb...
Includes: Supplementary data
Articles
Biochem J (2006) 399 (2): 343–350.
Published: 27 September 2006
... 6 2006 The Biochemical Society, London 2006 computer simulation enzyme mechanism hybrid potential phosphate ester protein phosphatase Protein phosphorylation plays a fundamental role in many cellular processes, such as signalling, growth, migration, proliferation...
Articles
Biochem J (2004) 384 (2): 437–447.
Published: 23 November 2004
... 2004 22 6 2004 23 8 2004 23 8 2004 The Biochemical Society, London 2004 argininosuccinate lyase catalysis δ crystallin enzyme mechanism mutagenesis δ Crystallin is the major soluble protein in the eye lenses of birds and terrestrial reptiles. This taxon-specific...
Articles
Biochem J (2004) 381 (3): 813–821.
Published: 27 July 2004
... 2003 14 4 2004 19 4 2004 19 4 2004 The Biochemical Society, London 2004 alginate Azotobacter vinelandii enzyme mechanism mannuronan C-5 epimerase time-resolved NMR Alginate is a widely used polysaccharide with many industrial applications. It is composed of two...
Articles
Biochem J (2002) 365 (3): 701–705.
Published: 01 August 2002
... distribution at the final stage of the reaction, preventing complete hydrolysis of the substrates. 1 e-mail h_nakatani@hotmail.com 3 12 2001 9 4 2002 19 4 2002 The Biochemical Society, London ©2002 2002 enzyme kinetics enzyme mechanism hyaluronan probabilistic model...
Articles
Biochem J (2002) 363 (3): 493–501.
Published: 24 April 2002
... Present address: Institute of Molecular Pathology, Dr. Bohr-Gasse 7, A-1030 Vienna, Austria. 2 To whom correspondence should be addressed (e-mail timothy.skern@univie.ac.at ). 26 11 2001 6 2 2002 20 2 2002 The Biochemical Society, London ©2002 2002 enzyme mechanism...
Articles
Biochem J (2000) 349 (3): 853–861.
Published: 25 July 2000
... dehydrogenases enzyme mechanism nucleotide specificity Biochem. J. (2000) 349, 853 861 (Printed in Great Britain) 853 Crystal structure of the NADP+-dependent aldehyde dehydrogenase from Vibrio harveyi : structural implications for cofactor specificity and affinity Bijan AHVAZI1, Rene COULOMBE1, Marc...
Articles
Biochem J (2000) 347 (3): 865–873.
Published: 25 April 2000
..., London © 2000 2000 affinity labelling enzyme mechanism glycanases mass spectrometry peptide analysis Biochem. J. (2000) 347, 865 873 (Printed in Great Britain) 865 Epoxyalkyl glycosides of D-xylose and xylo-oligosaccharides are active-site markers of xylanases from glycoside hydrolase family...