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1-41 of 41
Keywords: evolution
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Articles
Journal:
Biochemical Journal
Biochem J (2024) 481 (23): 1757–1770.
Published: 25 November 2024
... been proposed to result from chemistry, specifically C-F bond strength, or biology, largely negative selection from fluoride toxicity. Given natural evolution has many hurdles, this review advocates for a strategy of laboratory engineering and evolution. Enzymes identified to participate...
Articles
Journal:
Biochemical Journal
Biochem J (2019) 476 (18): 2607–2621.
Published: 24 September 2019
... conserved in plant CPSs involved in GA biosynthesis, providing insight into plant DTC evolution and assisting functional assignment. Even more strikingly, while GA biosynthesis arose independently in plant-associated bacteria and fungi, the catalytic base dyad also is specifically found in the relevant...
Articles
Journal:
Biochemical Journal
Biochem J (2016) 473 (14): 2011–2022.
Published: 12 July 2016
...) are a subset of this family that have enzymatic activity against hyalectan proteoglycans, the processing of which has important implications during development. This review explores the evolution, expression and developmental functions of the ADAMTS family, focusing on the ADAMTS hyalectanases...
Articles
Journal:
Biochemical Journal
Biochem J (2015) 467 (1): 17–35.
Published: 20 March 2015
... ] or on the catalytic mechanisms involved [ 18 – 20 ]. 1 Correspondence may be addressed to either of these authors (email [email protected] or [email protected] ). 17 11 2014 6 1 2015 9 1 2015 evolution glycoside hydrolase transglycosylation...
Articles
Journal:
Biochemical Journal
Biochem J (2013) 456 (1): 99–108.
Published: 24 October 2013
... 8 2013 © The Authors Journal compilation © 2013 Biochemical Society 2013 The antimicrobial mechanism of human RNases has been conserved along evolution and its activity is retained at an N-terminal antimicrobial domain. antimicrobial peptide drug discovery evolution innate...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2013) 453 (2): 155–166.
Published: 28 June 2013
... of regularly interspaced palindromic repeats (CRISPR) crystallography evolution protein structure repeat-associated mysterious protein (RAMP) CRISPRs (cluster of regularly interspaced palindromic repeats) are a prokaryotic defence mechanism against viral infection and horizontal gene transfer...
Includes: Supplementary data
Articles
Lars Ritscher, Eva Engemaier, Claudia Stäubert, Ines Liebscher, Philipp Schmidt, Thomas Hermsdorf, Holger Römpler, Angela Schulz, Torsten Schöneberg
Journal:
Biochemical Journal
Biochem J (2012) 443 (3): 841–850.
Published: 16 April 2012
... Biochemical Society 2012 chimaeric receptor evolution mutagenesis orphan G-protein-coupled receptor (GPCR) structure–function relationship GPR34 is an orphan GPCR (G-protein-coupled receptor) and was first discovered by mining GenBank® for novel GPCR sequences and homology cloning. It has...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2012) 443 (2): 477–484.
Published: 27 March 2012
...) domain RNA editing evolution leucyl-tRNA synthetase E. coli tRNA Leu GAG ( Ec tRNA Leu ) and A. aeolicus tRNA Leu GAG ( Aa tRNA Leu ) isoacceptor with an accepting activity of 1400 and 1350 pmol/ A 260 were prepared from overproducing strains constructed in our laboratory [ 8 , 18...
Includes: Supplementary data
Articles
Aleksander W. Roszak, Vladimíra Moulisová, Adhie D. P. Reksodipuro, Alastair T. Gardiner, Ritsuko Fujii, Hideki Hashimoto, Neil W. Isaacs, Richard J. Cogdell
Journal:
Biochemical Journal
Biochem J (2012) 442 (1): 27–37.
Published: 27 January 2012
... 2012 Blastochloris viridis evolution genetic drift integral membrane pigment–protein complex photosynthetic reaction centre purple photosynthetic bacteria reaction centre carotenoid reaction centre polypeptide sequence Photosynthetic RCs (reaction centres) are integral membrane...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2011) 433 (2): 263–276.
Published: 22 December 2010
... and related to published findings on the structure and function of fibrillins and LTBPs. These sequences give valuable insight into the evolution of TB domain proteins and suggest that the fibrillin domain organization emerged first, over 600 million years ago, prior to the divergence of Cnidaria...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2010) 431 (1): 13–22.
Published: 14 September 2010
...Kornelius Zeth; Marcus Thein Gram-negative bacteria and mitochondria are both covered by two distinct biological membranes. These membrane systems have been maintained during the course of evolution from an early evolutionary precursor. Both outer membranes accommodate channels of the porin family...
Articles
Catherine Johnson, Sandra Crowther, Margaret J. Stafford, David G. Campbell, Rachel Toth, Carol MacKintosh
Journal:
Biochemical Journal
Biochem J (2010) 427 (1): 69–78.
Published: 15 March 2010
... the class IIa histone deacetylases, whereas other protein families display differential regulation by 14-3-3s. We speculate that 14-3-3 dimers may have contributed to the evolution of such families, tailoring regulatory inputs to different physiological demands. 1 To whom correspondence should...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2010) 426 (3): 373–378.
Published: 24 February 2010
... 21 12 2009 © The Authors Journal compilation © 2010 Biochemical Society 2010 copper protein cupredoxin evolution haemocyanin (hemocyanin) keyhole-limpet-haemocyanin (KLH) Mollusca There is one exception to the standard architecture of molluscan haemocyanin FUs, namely the C...
Includes: Supplementary data
Articles
Roy M. Daniel, Michelle E. Peterson, Michael J. Danson, Nicholas C. Price, Sharon M. Kelly, Colin R. Monk, Cristina S. Weinberg, Matthew L. Oudshoorn, Charles K. Lee
Journal:
Biochemical Journal
Biochem J (2010) 425 (2): 353–360.
Published: 23 December 2009
... and reveals a new structurally localized and apparently universal mechanism for enzyme activity loss with increasing temperature, additional to denaturation. adaptation enzyme Equilibrium Model evolution kinetics temperature Saccharomyces cerevisiae α-glucosidase (E-SUCR; Megazyme...
Articles
Journal:
Biochemical Journal
Biochem J (2009) 419 (3): 585–593.
Published: 14 April 2009
... of the enzyme families involved in the generation and modification of HS were identified in Nematostella . Our results show that the enzymes are highly conserved throughout evolution, but the number of isoforms varies. Furthermore, the HS polymerases [Ext (exostosin) enzymes Ext1, Ext2 and Ext-like3] represent...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2009) 419 (1): 15–28.
Published: 13 March 2009
...Cyrus Chothia; Julian Gough It has been known for more than 35 years that, during evolution, new proteins are formed by gene duplications, sequence and structural divergence and, in many cases, gene combinations. The genome projects have produced complete, or almost complete, descriptions...
Articles
Journal:
Biochemical Journal
Biochem J (2009) 417 (3): 621–637.
Published: 16 January 2009
... (domain structure) and by how domains combine with others (domain organization). evolution fold superfamily organismal diversification protein domain proteome tripartite world Protein molecules are vital components of life. Together with functional RNA, they are primarily responsible...
Includes: Multimedia, Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2009) 417 (2): 449–455.
Published: 23 December 2008
...Rajesh Saha; Saumya Dasgupta; Gautam Basu; Siddhartha Roy aaRSs (aminoacyl-tRNA synthetases) are multi-domain proteins that have evolved by domain acquisition. The anti-codon binding domain was added to the more ancient catalytic domain during aaRS evolution. Unlike in eukaryotes, the anti-codon...
Articles
Journal:
Biochemical Journal
Biochem J (2009) 417 (1): 29–42.
Published: 12 December 2008
... it as religiously based, and forbade long-refuted ‘criticisms of evolution’ from introduction into public school classes. Much of the science of the trial was based on biochemistry; biochemists and other scientists have several important opportunities to improve scientific literacy and science education in American...
Articles
Felicity H. Alcock, J. Günter Grossmann, Ian E. Gentle, Vladimir A. Likić, Trevor Lithgow, Kostas Tokatlidis
Journal:
Biochemical Journal
Biochem J (2008) 409 (2): 377–387.
Published: 21 December 2007
... -value scores <10 −40 . © The Authors Journal compilation © 2008 Biochemical Society 2008 ADP/ATP carrier (AAC) evolution mitochondrion protein translocation small Tim chaperone SurA Mitochondria and α-proteobacteria share an ancestry with mitochondria derived from endosymbiotic...
Articles
Marta Manzoni, Paolo Colombi, Nadia Papini, Luana Rubaga, Natascia Tiso, Augusto Preti, Bruno Venerando, Guido Tettamanti, Roberto Bresciani, Francesco Argenton, Giuseppe Borsani, Eugenio Monti
Journal:
Biochemical Journal
Biochem J (2007) 408 (3): 395–406.
Published: 28 November 2007
... of sialidases together with their expression profile and their activity exerted on gangliosides of living cells indicate the biological relevance of this class of enzymes in zebrafish. comparative genomics evolution neuraminidase sialidase zebrafish The coding regions of neu3.1 , neu3.2...
Includes: Supplementary data
Articles
Fudi Wang, Adam P. Lothrop, Nicholas G. James, Tanya A. M. Griffiths, Lisa A. Lambert, Rachael Leverence, Igor A. Kaltashov, Nancy C. Andrews, Ross T. A. MacGillivray, Anne B. Mason
Journal:
Biochemical Journal
Biochem J (2007) 406 (1): 85–95.
Published: 26 July 2007
...). baby-hamster kidney cell (BHK cell) evolution inhibitor of carbonic anhydrase iron homoeostasis transferrin superfamily melanotransferrin CAs (carbonic anhydrases) constitute a ubiquitous family of enzymes found at high concentrations in various tissues, with a particularly high abundance...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2005) 392 (2): 299–307.
Published: 22 November 2005
... biosynthesis, enzyme regulation, regulation of the intracellular acyl-CoA pool size, donation of acyl-CoA esters for β-oxidation, vesicular trafficking, complex lipid synthesis and gene regulation. In the present study, we delineate the evolutionary history of ACBP to get a complete picture of its evolution...
Includes: Supplementary data
Articles
Guillaume RIVIÈRE, Annie MICHAUD, Laurence DELOFFRE, Franck VANDENBULCKE, Angélique LEVOYE, Christophe BRETON, Pierre CORVOL, Michel SALZET, Didier VIEAU
Journal:
Biochemical Journal
Biochem J (2004) 382 (2): 565–573.
Published: 24 August 2004
... of evolution and the situation encountered in more distant groups. Our model, the freshwater-living leech, Theromyzon tessulatum (Annelida; Clitellata; Hirudinida; Hirudinea; Rhynchobdellida; Glossiphoniidae), is an aquatic-bird ectoparasite; its life cycle has been divided into four stages according...
Articles
Journal:
Biochemical Journal
Biochem J (2004) 381 (3): 561–579.
Published: 27 July 2004
... in trypanosomatids (albeit with possibly only one of the domains active), indicates that fusion of genes initially coding for separate PFK-2 and FBPase-2 domains might have occurred early in evolution. In the enzyme homodimer, the PFK-2 domains come together in a head-to-head like fashion, whereas the FBPase-2...
Articles
Journal:
Biochemical Journal
Biochem J (2004) 379 (3): 541–552.
Published: 01 May 2004
... will appear in the EMBL, GenBank®, DDBJ and GSDB Nucleotide Sequence Databases under the accession number AY520571. 30 10 2003 18 12 2003 7 1 2004 7 1 2004 The Biochemical Society, London ©2004 2004 disulphide-bond-forming (Dsb) oxidoreductase evolution glutathione...
Articles
Journal:
Biochemical Journal
Biochem J (2003) 374 (1): 219–228.
Published: 15 August 2003
... metabolism evolution haemocyanin moulting cycle superoxide dismutase (SOD) Abbreviations used: DTPA, diethylenetriaminepenta-acetic acid; MT, metallothionein; SOD, superoxide dismutase; Cu,ZnSOD, copper/zinc SOD; cytCu,ZnSOD, cytosolic Cu,ZnSOD; ecCu,ZnSOD, extracellular Cu,ZnSOD; MnSOD...
Articles
Juan J. CALVETE, M. Paz MORENO-MURCIANO, R. David G. THEAKSTON, Dariusz G. KISIEL, Cezary MARCINKIEWICZ
Journal:
Biochemical Journal
Biochem J (2003) 372 (3): 725–734.
Published: 15 June 2003
... occurred through disulphide bond engineering. Key words: disintegrin, disulphide bond, evolution, protein sequence, snake venom protein. INTRODUCTION Crotalid and viperid venoms contain a large number of haemor- rhagic proteins. Haemorrhage is the result of the synergistic action of certain...
Articles
Jill A. COWING, Subathra POOPALASUNDARAM, Susan E. WILKIE, Phyllis R. ROBINSON, James K. BOWMAKER, David M. HUNT
Journal:
Biochemical Journal
Biochem J (2002) 367 (1): 129–135.
Published: 01 October 2002
... and that VS pigments have evolved separately from UVS pigments in the different vertebrate lineages. In this study, we have examined the mechanism of evolution of VS pigments in the mammalian lineage leading to present day ungulates (cow and pig). Amino acid sequence comparisons of the UVS pigments of teleost...
Articles
Journal:
Biochemical Journal
Biochem J (2002) 366 (1): 367–375.
Published: 15 August 2002
...Christoph GESERICK; Bertram WEISS; Wolf-Dieter SCHLEUNING; Bernard HAENDLER paired genes emerged early in evolution and code for homeobox transcription factors, having fundamental roles in various biological processes. We identified a novel human member of the paired -like class, which we named...
Articles
Peter J.M. STEENBAKKERS, Wimal UBHAYASEKERA, Harry J.A.M. GOOSSEN, Erik M.H.M. van LIEROP, Chris van der DRIFT, Godfried D. VOGELS, Sherry L. MOWBRAY, Huub J.M. Op den CAMP
Journal:
Biochemical Journal
Biochem J (2002) 365 (1): 193–204.
Published: 01 July 2002
... presented here are used to discuss evolution of glycoside hydrolase family 9 enzymes. 1 To whom correspondence should be addressed (e-mail [email protected] ). The nucleotide sequences included in this manuscript have been submitted to the GenBank ® , EMBL, DDBJ and GSDB Nucleotide Sequence...
Articles
Torun DUNÉR, J. Michael CONLON, Jyrki P. KUKKONEN, Karl E.O. ÅKERMAN, Yi-Lin YAN, John H. POSTLETHWAIT, Dan LARHAMMAR
Journal:
Biochemical Journal
Biochem J (2002) 364 (3): 817–824.
Published: 15 June 2002
...-mail [email protected] ). 15 8 2001 28 2 2002 8 4 2002 The Biochemical Society, London ©2002 2002 Ca 2+ chromosome G-protein-coupled receptor evolution teleost trout Abbreviations used: BK, bradykinin; B1, BK receptor B1; B2, BK receptor B2; bdkrb2 , zebrafish BK...
Articles
David C. LAMB, Kay FOWLER, Tobias KIESER, Nigel MANNING, Larissa M. PODUST, Michael R. WATERMAN, Diane E. KELLY, Steven L. KELLY
Journal:
Biochemical Journal
Biochem J (2002) 364 (2): 555–562.
Published: 01 June 2002
... The Biochemical Society, London ©2002 2002 cytochrome P450 evolution sterol Streptomyces transposon Abbreviations used: BSTFA, bis(trimethylsilyl)trifluoroacetamide; CYP, cytochrome P450; CYP51, sterol 14α-demethylase; NTA, nitrilotriacetic acid; ORF, open reading frame; 24-MDL, 24-methylene...
Articles
Journal:
Biochemical Journal
Biochem J (2000) 350 (3): 609–629.
Published: 08 September 2000
... are briefly reviewed. Evidence suggests that the biosynthetic pathways to the two carriers are largely distinct, suggesting the possibility of (ancient) separate origins rather than divergent evolution. It has recently been discovered that some eubacteria which gain energy by oxidation of C 1 compounds...
Articles
Antje LISCHKE, Christian KLEIN, York-Dieter STIERHOF, Michaela HEMPEL, Angela MEHLERT, Igor C. ALMEIDA, Michael A. J. FERGUSON, Peter OVERATH
Journal:
Biochemical Journal
Biochem J (2000) 345 (3): 693–700.
Published: 25 January 2000
... should be addressed (e-mail peter.overath@;tuebingen.mpg.de). 6 9 1999 5 11 1999 16 11 1999 The Biochemical Society, London © 2000 2000 antigenic variation evolution GPI anchors immune response Biochem. J. (2000) 345, 693 700 (Printed in Great Britain) 693 Isolation...
Articles
Journal:
Biochemical Journal
Biochem J (1999) 344 (3): 667–675.
Published: 08 December 1999
... indicate positive pressure to alter the amino acids in the V-type domain in evolution. Immunoblot analyses showed that mouse BIT and human BITα are predominantly expressed in the brain. On the bases of these findings we discuss the possibility that BIT contributes to the genetic individuality and diversity...
Articles
Giuseppe FIERMONTE, Vincenza DOLCE, Roberto ARRIGONI, Michael J. RUNSWICK, John E. WALKER, Ferdinando PALMIERI
Journal:
Biochemical Journal
Biochem J (1999) 344 (3): 953–960.
Published: 08 December 1999
... been demonstrated by Northern- and Western-blot analyses that the DIC is present in high amounts in liver and kidney, and at lower levels in all the other tissues analysed. The positions of introns contribute towards an understanding of the processes involved in the evolution of human genes for carrier...
Articles
Journal:
Biochemical Journal
Biochem J (1999) 344 (2): 385–390.
Published: 24 November 1999
... 6 1999 2 8 1999 8 9 1999 The Biochemical Society, London © 1999 1999 evolution exon/intron organization membrane-bound carbonic anhydrase secreted carbonic anhydrase Biochem. J. (1999) 344, 385 390 (Printed in Great Britain) 385 Structure of the carbonic anhydrase VI...
Articles
Tomohiko SUZUKI, Mika KAMIDOCHI, Naho INOUE, Hozumi KAWAMICHI, Yoichi YAZAWA, Takahiro FURUKOHRI, W. Ross ELLINGTON
Journal:
Biochemical Journal
Biochem J (1999) 340 (3): 671–675.
Published: 08 June 1999
... the evolution of phosphagen kinases: first at an early stage of phosphagen kinase evolution (its descendants are molluscan and arthropod AKs) and secondly from CK later in metazoan evolution. A comparison of the amino acid sequence around the guanidino specificity (GS) region (which is a possible candidate...
Articles
Lisa M. WRIGHT, Els J. M. VAN DAMME, Annick BARRE, Anthony K. ALLEN, Fred VAN LEUVEN, Colin D. REYNOLDS, Pierre ROUGE, Willy J. PEUMANS
Journal:
Biochemical Journal
Biochem J (1999) 340 (1): 299–308.
Published: 10 May 1999
... crystallographic analysis and molecular modelling studies have demonstrated close relationships in sequence and structure between these lectins and other monocot mannose-binding lectins. A refined model of the molecular evolution of the monocot mannose-binding lectins is proposed. Biochem. J. (1999) 340, 299 308...
Articles
Journal:
Biochemical Journal
Biochem J (1999) 337 (3): 425–431.
Published: 25 January 1999
... reductase Cochliobolus lunatus evolution fungi 17-hydroxysteroid dehydrogenase Biochem. J. (1999) 337, 425 431 (Printed in Great Britain) 425 A novel 17b-hydroxysteroid dehydrogenase in the fungus Cochliobolus lunatus : new insights into the evolution of steroid-hormone signalling Tea LANISC NIK RIZC...
