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Keywords: extracellular-signal-regulated kinase 1 and 2 (ERK1/ERK2)
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Articles
Angiotensin II-induced ERK1/ERK2 activation and protein synthesis are redox-dependent in glomerular mesangial cells
Available to PurchaseYves GORIN, Jill M. RICONO, Brent WAGNER, Nam-Ho KIM, Basant BHANDARI, Goutam Ghosh CHOUDHURY, Hanna E. ABBOUD
Journal:
Biochemical Journal
Biochem J (2004) 381 (1): 231–239.
Published: 22 June 2004
... targets of Ang II are the extracellular-signal-regulated kinases 1 and 2 (ERK1/ERK2). We demonstrate that Ang II activates ERK1/ERK2 via the AT 1 receptor. Arachidonic acid (AA) mimics the action of Ang II on ERK1/ERK2 and phospholipase A 2 inhibitors blocked Ang II-induced ERK1/ERK2 activation...
