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Keywords: extracellular-signal-related kinase (ERK)
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Articles

Thrombin inhibits Bim (Bcl-2-interacting mediator of cell death) expression and prevents serum-withdrawal-induced apoptosis via protease-activated receptor 1

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Claire J. CHALMERS, Kathryn BALMANNO, Kathryn HADFIELD, Rebecca LEY, Simon J. COOK
Journal: Biochemical Journal
Biochem J (2003) 375 (1): 99–109.
https://doi.org/10.1042/bj20030346
Published: 01 October 2003
... (protease-activated receptor 1 agonist peptide) was also able to protect cells from serum-withdrawal-induced apoptosis, suggesting that thrombin acts via PAR1 to prevent apoptosis. Key words: apoptosis, Bim, extracellular-signal-related kinase (ERK), protease-activated receptor 1 (PAR1), protein kinase B...
View articletitled, Thrombin inhibits Bim (Bcl-2-interacting mediator of cell death) expression and prevents serum-withdrawal-induced apoptosis via protease-activated receptor 1
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Articles

Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity

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A. Jane BARDWELL, Mahsa ABDOLLAHI, Lee BARDWELL
Journal: Biochemical Journal
Biochem J (2003) 370 (3): 1077–1085.
https://doi.org/10.1042/bj20021806
Published: 15 March 2003
... for binding to the same region of ERK2 via protein protein interactions that are crucial for kinase}phosphatase activity. Key words: docking-site peptide, Elk-1, extracellular-signal- related kinase (ERK), MAPK phosphatase (MKP), MAPK} ERK kinase (MEK), mitogen-activated protein kinase (MAPK). diverse range...
View articletitled, Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity
Open the PDF for Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity in another window