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Keywords: fatty acid synthesis
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Biochem J (2014) 459 (3): 489–503.
Published: 11 April 2014
... fatty acid synthesis in adipocytes. Total RNA was extracted by using TriPure isolation reagent (Roche Diagnostics) according to the manufacturer's instructions. First-strand cDNAs were synthesized from 1 μg of total RNA with random hexamer and ReverTra Ace reverse transcriptase (Toyobo...
Includes: Supplementary data
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Biochem J (2007) 403 (3): 473–481.
Published: 12 April 2007
... kinase). PKA phosphorylates HSL (hormone-sensitive lipase) at Ser 563 , Ser 659 and Ser 660 [ 4 ], two of which are critical sites for HSL activity [ 4 ]. Adrenaline also inhibits fatty acid synthesis via inhibition of ACC (acetyl-CoA carboxylase), the rate-limiting enzyme in fatty acid synthesis...
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Biochem J (2005) 392 (1): 201–209.
Published: 08 November 2005
... by switching off ATP-consuming pathways and switching on ATP-generating pathways when ATP is limiting. AMPK was first discovered as an activity that inhibited preparations of ACC1 (acetyl-CoA carboxylase), a regulator of cellular fatty acid synthesis. We report that NM23-H1/NDPK A and AMPK α1 are associated...
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Biochem J (2003) 369 (2): 351–356.
Published: 15 January 2003
...% of the maximal effect of insulin. This modest activation can be completely blocked by wortmannin alone, suggesting that PIG41 acts through only one of the pathways leading to the activation of pyruvate dehydrogenase. Key words: fatty acid synthesis, mitochondria, mitogen-activated protein kinase...
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