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1-8 of 8
Keywords: fatty acid synthesis
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Articles
Suppression of adipogenesis by valproic acid through repression of USF1-activated fatty acid synthesis in adipocytes
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2014) 459 (3): 489–503.
Published: 11 April 2014
... fatty acid synthesis in adipocytes. Total RNA was extracted by using TriPure isolation reagent (Roche Diagnostics) according to the manufacturer's instructions. First-strand cDNAs were synthesized from 1 μg of total RNA with random hexamer and ReverTra Ace reverse transcriptase (Toyobo...
Includes: Supplementary data
Articles
Adrenaline is a critical mediator of acute exercise-induced AMP-activated protein kinase activation in adipocytes
Available to PurchaseHo-Jin Koh, Michael F. Hirshman, Huamei He, Yangfeng Li, Yasuko Manabe, James A. Balschi, Laurie J. Goodyear
Journal:
Biochemical Journal
Biochem J (2007) 403 (3): 473–481.
Published: 12 April 2007
... kinase). PKA phosphorylates HSL (hormone-sensitive lipase) at Ser 563 , Ser 659 and Ser 660 [ 4 ], two of which are critical sites for HSL activity [ 4 ]. Adrenaline also inhibits fatty acid synthesis via inhibition of ACC (acetyl-CoA carboxylase), the rate-limiting enzyme in fatty acid synthesis...
Articles
Toxoplasma gondii acyl-lipid metabolism: de novo synthesis from apicoplast-generated fatty acids versus scavenging of host cell precursors
Available to PurchaseCordelia Bisanz, Olivier Bastien, Delphine Grando, Juliette Jouhet, Eric Maréchal, Marie-France Cesbron-Delauw
Journal:
Biochemical Journal
Biochem J (2006) 394 (1): 197–205.
Published: 27 January 2006
... detected by using the ECL system. acyl-lipid metabolism apicoplast fatty acid synthesis glycerol-3-phosphate Toxoplasma gondii Type II fatty acid synthase (FAS II) The unicellular eukaryote Toxoplasma gondii is an obligate intracellular parasite with an extremely broad host range...
Articles
A novel physical and functional association between nucleoside diphosphate kinase A and AMP-activated protein kinase α1 in liver and lung
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2005) 392 (1): 201–209.
Published: 08 November 2005
... by switching off ATP-consuming pathways and switching on ATP-generating pathways when ATP is limiting. AMPK was first discovered as an activity that inhibited preparations of ACC1 (acetyl-CoA carboxylase), a regulator of cellular fatty acid synthesis. We report that NM23-H1/NDPK A and AMPK α1 are associated...
Articles
Insulin stimulation of pyruvate dehydrogenase in adipocytes involves two distinct signalling pathways
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2003) 369 (2): 351–356.
Published: 15 January 2003
...% of the maximal effect of insulin. This modest activation can be completely blocked by wortmannin alone, suggesting that PIG41 acts through only one of the pathways leading to the activation of pyruvate dehydrogenase. Key words: fatty acid synthesis, mitochondria, mitogen-activated protein kinase...
Articles
Chicken ovalbumin upstream-promoter transcription factor and E-box-binding proteins enhance thyroid-hormone responsiveness of the malic enzyme gene in avian hepatocytes
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2002) 361 (2): 391–400.
Published: 08 January 2002
... 7 2001 22 10 2001 13 11 2001 The Biochemical Society, London ©2002 2002 enhanceosome fatty acid synthesis lipogenesis nuclear T3 receptor orphan receptor Abbreviations used: CEH, chick embryo hepatocytes; CEF, chick embryo fibroblasts; CAT, chloramphenicol...
Articles
Inhibition by long-chain acyl-CoAs of glucose 6-phosphate metabolism in plastids isolated from developing embryos of oilseed rape (Brassica napus L.)
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Journal:
Biochemical Journal
Biochem J (2000) 348 (1): 145–150.
Published: 09 May 2000
... isolated plastids. The binding of lcACoA esters by ACBP stimulated the utilization of Glc6P for fatty acid synthesis, starch synthesis and reductant supply via the oxidative pentose phosphate (OPP) pathway. Stimulation occurred at low (1-10 μ M) concentrations of ACBP. Pyruvate-dependent fatty acid...
Articles
Reaction mechanism of recombinant 3-oxoacyl-(acyl-carrier-protein) synthase III from Cuphea wrightii embryo, a fatty acid synthase type II condensing enzyme
Available to PurchaseAmine ABBADI, Monika BRUMMEL, Burkhardt S. SCHüTT, Mary B. SLABAUGH, Ricardo SCHUCH, Friedrich SPENER
Journal:
Biochemical Journal
Biochem J (2000) 345 (1): 153–160.
Published: 17 December 1999
... scanning revealed the involvement of Arg and Arg in KAS III catalysis. The results offer for the first time a detailed mechanism for a condensing reaction catalysed by a FAS type II condensing enzyme. Key words: ACP, active-site residues, fatty acid synthesis, protein engineering. transfer of the acyl...