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Keywords: fibulin-5
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Articles
Fibulin-5 binds urokinase-type plasminogen activator and mediates urokinase-stimulated β1-integrin-dependent cell migration
Available to PurchaseAlexander Kapustin, Victoria Stepanova, Natalia Aniol, Douglas B. Cines, Alexei Poliakov, Serge Yarovoi, Tatiana Lebedeva, Robin Wait, Grigory Ryzhakov, Yelena Parfyonova, Yaroslav Gursky, Hiromi Yanagisawa, Mikhail Minashkin, Robert Beabealashvilli, Alexander Vorotnikov, Alex Bobik, Vsevolod Tkachuk
Journal:
Biochemical Journal
Biochem J (2012) 443 (2): 491–503.
Published: 27 March 2012
...) which activate intracellular signalling pathways. In the present paper we report that uPA-mediated cell migration requires an interaction with fibulin-5. uPA stimulates migration of wild-type MEFs (mouse embryonic fibroblasts) ( Fbln5 +/+ MEFs), but has no effect on fibulin-5-deficient ( Fbln5...
Includes: Supplementary data
Articles
Fibulin-5 binds human smooth-muscle cells through α5β1 and α4β1 integrins, but does not support receptor activation
Available to PurchaseAmanda C. Lomas, Kieran T. Mellody, Lyle J. Freeman, Daniel V. Bax, C. Adrian Shuttleworth, Cay M. Kielty
Journal:
Biochemical Journal
Biochem J (2007) 405 (3): 417–428.
Published: 13 July 2007
...Amanda C. Lomas; Kieran T. Mellody; Lyle J. Freeman; Daniel V. Bax; C. Adrian Shuttleworth; Cay M. Kielty Fibulin-5, an extracellular matrix glycoprotein expressed in elastin-rich tissues, regulates vascular cell behaviour and elastic fibre deposition. Recombinant full-length human fibulin-5...
Articles
Fibulin-5 interacts with fibrillin-1 molecules and microfibrils
Available to PurchaseLyle J. FREEMAN, Amanda LOMAS, Nigel HODSON, Michael J. SHERRATT, Kieran T. MELLODY, Anthony S. WEISS, Adrian SHUTTLEWORTH, Cay M. KIELTY
Journal:
Biochemical Journal
Biochem J (2005) 388 (1): 1–5.
Published: 10 May 2005
...Lyle J. FREEMAN; Amanda LOMAS; Nigel HODSON; Michael J. SHERRATT; Kieran T. MELLODY; Anthony S. WEISS; Adrian SHUTTLEWORTH; Cay M. KIELTY Fibulin-5 plays an important role in elastic fibre formation in vivo . We have investigated the molecular interactions between fibulin-5 and components...
